Parasite‐mediated selection against Inbred Soay sheep in a free‐living island populaton
DW Coltman, JG Pilkington, JA Smith… - Evolution, 1999 - Wiley Online Library
Parasites are thought to provide a selective force capable of promoting genetic variation in
natural populations. One rarely considered pathway for this action is via parasite‐mediated …
natural populations. One rarely considered pathway for this action is via parasite‐mediated …
Life history trade-offs at a single locus maintain sexually selected genetic variation
Sexual selection, through intra-male competition or female choice, is assumed to be a
source of strong and sustained directional selection in the wild 1 , 2 . In the presence of such …
source of strong and sustained directional selection in the wild 1 , 2 . In the presence of such …
Genome‐wide association mapping identifies the genetic basis of discrete and quantitative variation in sexual weaponry in a wild sheep population
…, JW Kijas, D Beraldi, JG Pilkington… - Molecular …, 2011 - Wiley Online Library
Understanding the genetic architecture of phenotypic variation in natural populations is a
fundamental goal of evolutionary genetics. Wild Soay sheep (Ovis aries) have an inherited …
fundamental goal of evolutionary genetics. Wild Soay sheep (Ovis aries) have an inherited …
Fitness correlates of heritable variation in antibody responsiveness in a wild mammal
AL Graham, AD Hayward, KA Watt, JG Pilkington… - Science, 2010 - science.org
A functional immune system is important for survival in natural environments, where individuals
are frequently exposed to parasites. Yet strong immune responses may have fitness …
are frequently exposed to parasites. Yet strong immune responses may have fitness …
Life history correlates of oxidative damage in a free-living mammal population
1. Reactive oxygen species, produced as a by-product of normal metabolism, can cause
intracellular damage and negatively impact on cell function. Such oxidative damage has been …
intracellular damage and negatively impact on cell function. Such oxidative damage has been …
Estimating quantitative genetic parameters in wild populations: a comparison of pedigree and genomic approaches
C Bérénos, PA Ellis, JG Pilkington… - Molecular …, 2014 - Wiley Online Library
The estimation of quantitative genetic parameters in wild populations is generally limited by
the accuracy and completeness of the available pedigree information. Using relatedness at …
the accuracy and completeness of the available pedigree information. Using relatedness at …
Live fast, die young: trade‐offs between fitness components and sexually antagonistic selection on weaponry in Soay sheep
MR Robinson, JG Pilkington, TH Clutton‐Brock… - …, 2006 - Wiley Online Library
Males are predicted to compete for reproductive opportunities, with sexual selection driving
the evolution of large body size and weaponry through the advantage they confer for access …
the evolution of large body size and weaponry through the advantage they confer for access …
Lifelong leukocyte telomere dynamics and survival in a free‐living mammal
J Fairlie, R Holland, JG Pilkington, JM Pemberton… - Aging cell, 2016 - Wiley Online Library
Telomeres play a fundamental role in the maintenance of genomic integrity at a cellular level,
and average leukocyte telomere length ( LTL ) has been proposed as a biomarker of …
and average leukocyte telomere length ( LTL ) has been proposed as a biomarker of …
[HTML][HTML] Natural selection on individual variation in tolerance of gastrointestinal nematode infection
Hosts may mitigate the impact of parasites by two broad strategies: resistance, which limits
parasite burden, and tolerance, which limits the fitness or health cost of increasing parasite …
parasite burden, and tolerance, which limits the fitness or health cost of increasing parasite …
[HTML][HTML] Asynchrony of senescence among phenotypic traits in a wild mammal population
The degree to which changes in lifespan are coupled to changes in senescence in different
physiological systems and phenotypic traits is a central question in biogerontology. It is …
physiological systems and phenotypic traits is a central question in biogerontology. It is …