Deoxycorticosterone Upregulates PDS (Slc26a4) in Mouse Kidney: Role of Pendrin in Mineralocorticoid-Induced Hypertension

JW Verlander, KA Hassell, IE Royaux, DM Glapion… - …, 2003 - Am Heart Assoc
Pendrin is an anion exchanger expressed along the apical plasma membrane and apical
cytoplasmic vesicles of type B and of non-A, non-B intercalated cells of the distal convoluted …

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

…, S Breton, JW Verlander… - Proceedings of the …, 2017 - National Acad Sciences
Prior RNA sequencing (RNA-seq) studies have identified complete transcriptomes for most
renal epithelial cell types. The exceptions are the cell types that make up the renal collecting …

NaCl Restriction Upregulates Renal Slc26a4 Through Subcellular Redistribution: Role in Cl Conservation

…, DM Glapion, LA Everett, ED Green, JW Verlander - …, 2004 - Am Heart Assoc
Slc26a4 (Pds, pendrin) is an anion transporter expressed in the apical region of type B and
non-A, non-B intercalated cells of the distal nephron. It is upregulated by aldosterone …

[HTML][HTML] Renal ammonia metabolism and transport

ID Weiner, JW Verlander - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
Renal ammonia metabolism and transport mediates a central role in acid-base homeostasis.
In contrast to most renal solutes, the majority of renal ammonia excretion derives from …

Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model

…, L Adorini, M Pruzanski, JB Kopp, JW Verlander… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE The pathogenesis of diabetic nephropathy is complex and involves activation of
multiple pathways leading to kidney damage. An important role for altered lipid metabolism …

Role of NH3 and NH4+ transporters in renal acid-base transport

ID Weiner, JW Verlander - American Journal of Physiology …, 2011 - journals.physiology.org
Renal ammonia excretion is the predominant component of renal net acid excretion. The
majority of ammonia excretion is produced in the kidney and then undergoes regulated …

Localization of pendrin in mouse kidney

…, JY Chang, GL Shipley, JW Verlander - American Journal …, 2003 - journals.physiology.org
Pendrin is an anion exchanger expressed in type B intercalated cells of the cortical collecting
duct (CCD). Whether pendrin localizes to other nephron segments with intercalated cells is …

Ammonia transporters and their role in acid-base balance

ID Weiner, JW Verlander - Physiological reviews, 2017 - journals.physiology.org
Acid-base homeostasis is critical to maintenance of normal health. Renal ammonia excretion
is the quantitatively predominant component of renal net acid excretion, both under basal …

Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney

JW Verlander, RT Miller, AE Frank… - American Journal …, 2003 - journals.physiology.org
Ammonia is both produced and transported by renal epithelial cells, and it regulates renal
ion transport. Recent studies have identified a family of putative ammonium transporters; …

Localization of the thiazide sensitive Na-Cl cotransporter, rTSC1, in the rat kidney

MD Plotkin, MR Kaplan, JW Verlander, WS Lee… - Kidney international, 1996 - Elsevier
… CRAYEN MIL, THOENES W: Architecture and cell structures in the distal nephron of the rat
kidney. Cytobiologie 17:197–211, 1978 16. DORUP J: Ultrastructure of distal nephron cells in …