Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway
Objective Neutrophils are prominent components of solid tumours and exhibit distinct
phenotypes in different tumour microenvironments. However, the nature, regulation, function and …
phenotypes in different tumour microenvironments. However, the nature, regulation, function and …
Efficacy, safety, and immunogenicity of an oral recombinant Helicobacter pylori vaccine in children in China: a randomised, double-blind, placebo-controlled, phase 3 …
…, C Wu, DH Li, P Luo, H Zeng, WJ Zhang, JY Zhang… - The Lancet, 2015 - thelancet.com
Background Helicobacter pylori is one of the most common gastric pathogens, affecting at
least half the world's population, and is strongly associated with gastritis, peptic ulcer, gastric …
least half the world's population, and is strongly associated with gastritis, peptic ulcer, gastric …
Edge detection of images based on improved Sobel operator and genetic algorithms
Z Jin-Yu, C Yan, H Xian-Xiang - 2009 International Conference …, 2009 - ieeexplore.ieee.org
Edge detection of images is a classical problem in computer vision and image processing.
The key of edge detection is the choice of threshold; the choice of threshold directly …
The key of edge detection is the choice of threshold; the choice of threshold directly …
Helicobacter pylori-induced Th17 responses modulate Th1 cell responses, benefit bacterial growth, and contribute to pathology in mice
CD4+ T cell responses are critical for the pathogenesis of Helicobacter pylori infection. The
present study evaluated the role of the Th17 subset in H. pylori infection. H. pylori infection …
present study evaluated the role of the Th17 subset in H. pylori infection. H. pylori infection …
A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells
This study described a modified rat model of bone cancer pain. Syngeneic Walker 256
mammary gland carcinoma cells were injected into the tibia medullary cavity via intercondylar …
mammary gland carcinoma cells were injected into the tibia medullary cavity via intercondylar …
CD8+ T cells that produce interleukin-17 regulate myeloid-derived suppressor cells and are associated with survival time of patients with gastric cancer
BACKGROUND & AIMS: CD8 + T cells that produce interleukin (IL)-17 (Tc17 cells) promote
inflammation and have been identified in tumors. We investigated their role in the …
inflammation and have been identified in tumors. We investigated their role in the …
Increased intratumoral IL-22-producing CD4+ T cells and Th22 cells correlate with gastric cancer progression and predict poor patient survival
IL-22-producing CD4 + T cells (IL-22 + CD4 + T cells) and Th22 cells (IL-22 + IL-17 − IFN-γ
− CD4 + T cells) represent newly discovered T-cell subsets, but their nature, regulation, and …
− CD4 + T cells) represent newly discovered T-cell subsets, but their nature, regulation, and …
Compromised autophagy by MIR30Bbenefits the intracellular survival of Helicobacter pylori
…, Y Zhuang, Q Li, HG Wang, Y Fang, B Yu, JY Zhang… - Autophagy, 2012 - Taylor & Francis
Helicobacter pylori evade immune responses and achieve persistent colonization in the
stomach. However, the mechanism by which H. pylori infections persist is not clear. In this study, …
stomach. However, the mechanism by which H. pylori infections persist is not clear. In this study, …
Tumor-associated monocytes/macrophages impair NK-cell function via TGFβ1 in human gastric cancer
L Peng, J Zhang, Y Teng, Y Zhao, T Wang, F Mao… - Cancer immunology …, 2017 - AACR
Natural killer (NK) cells are a major component of the host antitumor immune response in
human cancer. However, the nature, functional regulation, and clinical relevance of NK cells in …
human cancer. However, the nature, functional regulation, and clinical relevance of NK cells in …
[HTML][HTML] Ovariectomy results in variable changes in nociception, mood and depression in adult female rats
Decline in the ovarian hormones with menopause may influence somatosensory, cognitive,
and affective processing. The present study investigated whether hormonal depletion alters …
and affective processing. The present study investigated whether hormonal depletion alters …