Ageing is characterized by the functional decline of tissues and organs and the increased
risk of ageing-associated disorders. Several ‘rejuvenating’ interventions have been proposed …

Background The pneumonia caused by the 2019 novel coronavirus (SARS-CoV-2, also called
2019-nCoV) recently break out in Wuhan, China, and was named as COVID-19. With the …

SIRT6 belongs to the mammalian homologs of Sir2 histone NAD+-dependent deacylase
family. In rodents, SIRT6 deficiency leads to aging-associated degeneration of mesodermal …

Targeted genome editing via engineered nucleases is an exciting area of biomedical research
and holds potential for clinical applications. Despite rapid advances in the field, in vivo …

Fucoxanthin, an allenic carotenoid, can be isolated from edible brown seaweeds. Recent
studies have reported that fucoxanthin has many physiological functions and biological …

Hutchinson–Gilford progeria syndrome (HGPS) is a rare and fatal human premature ageing
disease 1 , 2 , 3 , 4 , 5 , characterized by premature arteriosclerosis and degeneration of …

Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

The amendment of biochar for soil bioremediation can improve soil conditions, influence
soil microbial community, and achieve co-application of biochar-microbe to promote the …

Background Heightened surveillance of acute febrile illness in China since 2009 has led to
the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an unknown …

Constitutively activated NF-κB occurs in many inflammatory and tumor tissues. Does it interfere
with anti-inflammatory or anti-tumor signaling pathway? Here, we report that NF-κB p65 …