The triangular correlation heatmap aiming to visualize the linkage disequilibrium (LD)
pattern and haplotype block structure of SNPs is ubiquitous component of population-based …

Background COVID-19 characterized by refractory hypoxemia increases patient mortality
because of immunosuppression effects. This study aimed to evaluate the efficacy of …

Arterial media calcification is one of the major complications of diabetes mellitus, which is
related to oxidative stress and apoptosis. Mitophagy is a special regulation of mitochondrial …

Background Fibrotic remodeling is an essential aspect of heart failure. Human kallistatin (KS,
mouse Serpina3c homologs) inhibits fibrosis after myocardial infarction (MI) but the specific …

Extracellular matrix (ECM) exerts a series of biological functions and contributes to almost
30% of the osteogenic process. Periostin is a secreted protein that can alter ECM remodeling …

We have synthesized and evaluated a new series of acyclic P4-benzoxaborole-based HCV
NS3 protease inhibitors. Structure–activity relationships were investigated, leading to the …

Ferroptosis plays an important role in ischemia-reperfusion (I/R)-induced cardiac injury and
there are many defects in current targeted delivery of miRNAs for the treatment of ferroptosis. …

The lung plays a vital role in maintaining homeostasis, as it is responsible for the exchange
of oxygen and carbon dioxide. Pulmonary homeostasis is maintained by a network of tissue-…

The macrocyclic urea 2, a byproduct in the synthesis of benzoxaborole 1, was identified to
be a novel and potent HCV protease inhibitor. We further explored this motif by synthesizing …

… Zhi-feng Liu and Jing-jing Ji contributed equally to this work. … Zhi-feng Liu and Jing-jing Ji
contributed equally to this work.… Zhi-feng Liu and Jing-jing Ji contributed equally to this work. …