User profiles for Jingheng Zhou

Jingheng Zhou

Contract Scientist, NIEHS, NIH
Verified email at nih.gov
Cited by 1763

[PDF][PDF] A genetically encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice

F Sun, J Zeng, M Jing, J Zhou, J Feng, SF Owen, Y Luo… - Cell, 2018 - cell.com
Dopamine (DA) is a central monoamine neurotransmitter involved in many physiological and
pathological processes. A longstanding yet largely unmet goal is to measure DA changes …

Next-generation GRAB sensors for monitoring dopaminergic activity in vivo

F Sun, J Zhou, B Dai, T Qian, J Zeng, X Li, Y Zhuo… - Nature …, 2020 - nature.com
Dopamine (DA) plays a critical role in the brain, and the ability to directly measure
dopaminergic activity is essential for understanding its physiological functions. We therefore …

[PDF][PDF] A genetically encoded fluorescent sensor for rapid and specific in vivo detection of norepinephrine

J Feng, C Zhang, JE Lischinsky, M Jing, J Zhou… - Neuron, 2019 - cell.com
Norepinephrine (NE) is a key biogenic monoamine neurotransmitter involved in a wide range
of physiological processes. However, its precise dynamics and regulation remain poorly …

[PDF][PDF] Spectrally resolved fiber photometry for multi-component analysis of brain circuits

C Meng, J Zhou, A Papaneri, T Peddada, K Xu, G Cui - Neuron, 2018 - cell.com
To achieve simultaneous measurement of multiple cellular events in molecularly defined
groups of neurons in vivo, we designed a spectrometer-based fiber photometry system that …

[HTML][HTML] Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction

…, J Ma, J Guo, J Tan, A Dong, K He, J Zhou… - Nature …, 2022 - nature.com
Endocannabinoid (eCB), 2-arachidonoyl-glycerol (2-AG), the most abundant eCB in the
brain, regulates diverse neural functions. Here we linked multiple homozygous loss-of-function …

Chemogenetic stimulation of tonic locus coeruleus activity strengthens the default mode network

EA Oyarzabal, LM Hsu, M Das, THH Chao, J Zhou… - Science …, 2022 - science.org
The default mode network (DMN) of the brain is functionally associated with a wide range of
behaviors. In this study, we used functional magnetic resonance imaging (fMRI), positron …

Monitoring norepinephrine release in vivo using next-generation GRABNE sensors

J Feng, H Dong, JE Lischinsky, J Zhou, F Deng… - Neuron, 2023 - cell.com
Norepinephrine (NE) is an essential biogenic monoamine neurotransmitter. The first-generation
NE sensor makes in vivo, real-time, cell-type-specific and region-specific NE detection …

Septal cholinergic neurons gate hippocampal output to entorhinal cortex via oriens lacunosum moleculare interneurons

J Haam, J Zhou, G Cui, JL Yakel - Proceedings of the …, 2018 - National Acad Sciences
Neuromodulation of neural networks, whereby a selected circuit is regulated by a particular
modulator, plays a critical role in learning and memory. Among neuromodulators, …

Incorporating charged Ag@ MOFs to boost the antibacterial and filtration properties of porous electrospinning polylactide films

Z Yue, J Zhou, X Du, L Wu, J Wang, X Wang - International Journal of …, 2023 - Elsevier
Faced with the pollution caused by particulate matter (PM) in the air, the prevalence of
infectious diseases, and the environmental burden by use of nondegradable polymers, the …

[PDF][PDF] Spectral fiber photometry derives hemoglobin concentration changes for accurate measurement of fluorescent sensor activity

…, Y Yang, TW Wang, SH Lee, EA Oyarzabal, J Zhou… - Cell reports …, 2022 - cell.com
Fiber photometry is an emerging technique for recording fluorescent sensor activity in the
brain. However, significant hemoglobin absorption artifacts in fiber photometry data may be …