User profiles for Jingheng Zhou
Jingheng ZhouContract Scientist, NIEHS, NIH Verified email at nih.gov Cited by 1763 |
[PDF][PDF] A genetically encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice
Dopamine (DA) is a central monoamine neurotransmitter involved in many physiological and
pathological processes. A longstanding yet largely unmet goal is to measure DA changes …
pathological processes. A longstanding yet largely unmet goal is to measure DA changes …
Next-generation GRAB sensors for monitoring dopaminergic activity in vivo
Dopamine (DA) plays a critical role in the brain, and the ability to directly measure
dopaminergic activity is essential for understanding its physiological functions. We therefore …
dopaminergic activity is essential for understanding its physiological functions. We therefore …
[PDF][PDF] A genetically encoded fluorescent sensor for rapid and specific in vivo detection of norepinephrine
Norepinephrine (NE) is a key biogenic monoamine neurotransmitter involved in a wide range
of physiological processes. However, its precise dynamics and regulation remain poorly …
of physiological processes. However, its precise dynamics and regulation remain poorly …
[PDF][PDF] Spectrally resolved fiber photometry for multi-component analysis of brain circuits
To achieve simultaneous measurement of multiple cellular events in molecularly defined
groups of neurons in vivo, we designed a spectrometer-based fiber photometry system that …
groups of neurons in vivo, we designed a spectrometer-based fiber photometry system that …
[HTML][HTML] Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
Endocannabinoid (eCB), 2-arachidonoyl-glycerol (2-AG), the most abundant eCB in the
brain, regulates diverse neural functions. Here we linked multiple homozygous loss-of-function …
brain, regulates diverse neural functions. Here we linked multiple homozygous loss-of-function …
Chemogenetic stimulation of tonic locus coeruleus activity strengthens the default mode network
The default mode network (DMN) of the brain is functionally associated with a wide range of
behaviors. In this study, we used functional magnetic resonance imaging (fMRI), positron …
behaviors. In this study, we used functional magnetic resonance imaging (fMRI), positron …
Monitoring norepinephrine release in vivo using next-generation GRABNE sensors
J Feng, H Dong, JE Lischinsky, J Zhou, F Deng… - Neuron, 2023 - cell.com
Norepinephrine (NE) is an essential biogenic monoamine neurotransmitter. The first-generation
NE sensor makes in vivo, real-time, cell-type-specific and region-specific NE detection …
NE sensor makes in vivo, real-time, cell-type-specific and region-specific NE detection …
Septal cholinergic neurons gate hippocampal output to entorhinal cortex via oriens lacunosum moleculare interneurons
J Haam, J Zhou, G Cui, JL Yakel - Proceedings of the …, 2018 - National Acad Sciences
Neuromodulation of neural networks, whereby a selected circuit is regulated by a particular
modulator, plays a critical role in learning and memory. Among neuromodulators, …
modulator, plays a critical role in learning and memory. Among neuromodulators, …
Incorporating charged Ag@ MOFs to boost the antibacterial and filtration properties of porous electrospinning polylactide films
Z Yue, J Zhou, X Du, L Wu, J Wang, X Wang - International Journal of …, 2023 - Elsevier
Faced with the pollution caused by particulate matter (PM) in the air, the prevalence of
infectious diseases, and the environmental burden by use of nondegradable polymers, the …
infectious diseases, and the environmental burden by use of nondegradable polymers, the …
[PDF][PDF] Spectral fiber photometry derives hemoglobin concentration changes for accurate measurement of fluorescent sensor activity
Fiber photometry is an emerging technique for recording fluorescent sensor activity in the
brain. However, significant hemoglobin absorption artifacts in fiber photometry data may be …
brain. However, significant hemoglobin absorption artifacts in fiber photometry data may be …