[PDF][PDF] CD10+ GPR77+ cancer-associated fibroblasts promote cancer formation and chemoresistance by sustaining cancer stemness
…, M Wang, M Luo, Y Xing, F Chen, D Huang, J Zhao… - Cell, 2018 - cell.com
Carcinoma-associated fibroblasts (CAFs) are abundant and heterogeneous stromal cells in
tumor microenvironment that are critically involved in cancer progression. Here, we …
tumor microenvironment that are critically involved in cancer progression. Here, we …
Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells
…, D Yin, D Lin, PP Wong, D Huang, Y Xing, J Zhao… - Nature cell …, 2019 - nature.com
Metabolic reprogramming is a hallmark of cancer. Here, we demonstrate that tumour-associated
macrophages (TAMs) enhance the aerobic glycolysis and apoptotic resistance of breast …
macrophages (TAMs) enhance the aerobic glycolysis and apoptotic resistance of breast …
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death
…, J Chen, L Yang, Q Ouyang, J Li, L Lao, J Zhao… - Nature …, 2018 - nature.com
Activation-induced cell death (AICD) of T lymphocytes can be exploited by cancers to escape
immunological destruction. We demonstrated that tumor-specific cytotoxic T lymphocytes (…
immunological destruction. We demonstrated that tumor-specific cytotoxic T lymphocytes (…
[HTML][HTML] Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
…, J Zhao, SA Shahane, M Attene-Ramos, T Zhao… - Nature …, 2016 - nature.com
Target-specific, mechanism-oriented in vitro assays post a promising alternative to traditional
animal toxicology studies. Here we report the first comprehensive analysis of the Tox21 …
animal toxicology studies. Here we report the first comprehensive analysis of the Tox21 …
Effect of microplastic size on the adsorption behavior and mechanism of triclosan on polyvinyl chloride
Microplastics in water environment and its ability to load various environmental pollutants
have attracted wide attention in recent years. However, effect of microplastic size on the …
have attracted wide attention in recent years. However, effect of microplastic size on the …
Interfacial interaction between micro/nanoplastics and typical PPCPs and nanoplastics removal via electrosorption from an aqueous solution
Micro/nanoplastics have raised worldwide concern with extensive research on its transfer,
toxicity and removal. However, the primary environmental process-adsorption of nanoplastics …
toxicity and removal. However, the primary environmental process-adsorption of nanoplastics …
[PDF][PDF] Immune checkpoint inhibition overcomes ADCP-induced immunosuppression by macrophages
S Su, J Zhao, Y Xing, X Zhang, J Liu, Q Ouyang… - Cell, 2018 - cell.com
Antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis
(ADCP) critically contribute to the efficacy of anti-tumor therapeutic antibodies. We report …
(ADCP) critically contribute to the efficacy of anti-tumor therapeutic antibodies. We report …
[PDF][PDF] Localization of a gene for familial hemophagocytic lymphohistiocytosis at chromosome 9q21. 3-22 by homozygosity mapping
Familial hemophagocytic lymphohistiocytosis (FHL), also known as familial erythrophagocytic
lymphohistiocytosis and familial histiocytic reticulosis, is a rare autosomal recessive …
lymphohistiocytosis and familial histiocytic reticulosis, is a rare autosomal recessive …
[HTML][HTML] Tox21Challenge to build predictive models of nuclear receptor and stress response pathways as mediated by exposure to environmental chemicals and …
Tens of thousands of chemicals with poorly understood biological properties are released into
the environment each day. High-throughput screening (HTS) is potentially a more efficient …
the environment each day. High-throughput screening (HTS) is potentially a more efficient …
Ionically cross-linked sodium alginate/ĸ-carrageenan double-network gel beads with low-swelling, enhanced mechanical properties, and excellent adsorption …
Double-network gel is composed of two kinds of crosslinked organic/inorganic networks,
which has a good prospect of environmental application and its application in the antibiotic …
which has a good prospect of environmental application and its application in the antibiotic …