FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao… - Nature …, 2020 - nature.com
Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells
assembles large complexes called inflammasomes, which activate inflammatory caspases to …

Strong El Niño events and nonlinear dynamical heating

…, SI An, A Timmermann, J Zhao - Geophysical research …, 2003 - Wiley Online Library
We present evidence showing that the nonlinear dynamic heating (NDH) in the tropical Pacific
ocean heat budget is essential in the generation of intense El Niño events as well as the …

Influences of nanoparticle zinc oxide on acutely isolated rat hippocampal CA3 pyramidal neurons

J Zhao, L Xu, T Zhang, G Ren, Z Yang - Neurotoxicology, 2009 - Elsevier
The effects of zinc oxide nanoparticles (nano-ZnO) on the properties of voltage-dependent
sodium, potassium currents and evoked action potentials were studied in acutely isolated rat …

Ferulic acid protects against heat stress-induced intestinal epithelial barrier dysfunction in IEC-6 cells via the PI3K/Akt-mediated Nrf2/HO-1 signaling pathway

S He, Y Guo, J Zhao, X Xu, J Song… - International Journal of …, 2018 - Taylor & Francis
Purpose: Intestinal epithelial barrier dysfunction is crucial in the pathogenesis of intestinal
and systemic diseases. Ferulic acid (FA) possesses promising antioxidant activities. In a …

[HTML][HTML] Gamma delta T cells and their pathogenic role in psoriasis

C Qi, Y Wang, P Li, J Zhao - Frontiers in immunology, 2021 - frontiersin.org
γδT cells are an unconventional population of T lymphocytes that play an indispensable
role in host defense, immune surveillance, and homeostasis of the immune system. They …

[HTML][HTML] Ferulic acid ameliorates lipopolysaccharide-induced barrier dysfunction via microRNA-200c-3p-mediated activation of PI3K/AKT pathway in Caco-2 cells

S He, Y Guo, J Zhao, X Xu, N Wang… - Frontiers in pharmacology, 2020 - frontiersin.org
Intestinal barrier dysfunction is an important clinical problem in various acute and chronic
pathological conditions. Ferulic acid (FA) can attenuate the intestinal epithelial barrier …

Association between vitamin D deficiency and antepartum and postpartum depression: a systematic review and meta-analysis of longitudinal studies

J Wang, N Liu, W Sun, D Chen, J Zhao… - Archives of gynecology …, 2018 - Springer
Purpose The two previous reviews performed on the association of vitamin D deficiency in
pregnancy with antepartum and postpartum depression were limited in reporting forms as …

[HTML][HTML] Paeoniflorin inhibits imiquimod-induced psoriasis in mice by regulating Th17 cell response and cytokine secretion

J Zhao, T Di, Y Wang, Y Wang, X Liu, D Liang… - European journal of …, 2016 - Elsevier
Paeoniflorin (PF) is the main active ingredients of radix paeoniae rubra and radix paeoniae
alba, which are used widely in Traditional Chinese Medicine. This study aimed to assess the …

Combining network pharmacology, RNA-seq, and metabolomics strategies to reveal the mechanism of Cimicifugae Rhizoma-Smilax glabra Roxb herb pair for the …

…, YJ Meng, Y Wang, N Zhao, XW Zhang, P Li, J Zhao - Phytomedicine, 2022 - Elsevier
… The study was designed by Ping Li and Jingxia Zhao. Cong Qi and Fang Feng performed …
, Ning Zhao, and XiaWei Zhang. XueQing Hu wrote the manuscript. Ping Li and Jingxia Zhao

[HTML][HTML] Paeonol ameliorates imiquimod-induced psoriasis-like skin lesions in BALB/c mice by inhibiting the maturation and activation of dendritic cells

…, M Wang, X Xie, T Di, J Zhao… - International …, 2017 - spandidos-publications.com
Paeonol, an active component derived from the traditional Chinese medicine Cortex Moutan,
possesses anti-inflammatory, analgesic, antioxidant and anti-allergic properties. Psoriasis …