Genetic evidence supports demic diffusion of Han culture

…, Y He, F Li, Y Gao, X Mao, L Zhang, J Qian, J Tan… - Nature, 2004 - nature.com
The spread of culture and language in human populations is explained by two alternative
models: the demic diffusion model, which involves mass movement of people; and the cultural …

A genome-wide search for signals of high-altitude adaptation in Tibetans

S Xu, S Li, Y Yang, J Tan, H Lou, W Jin… - Molecular biology …, 2011 - academic.oup.com
Genetic studies of Tibetans, an ethnic group with a long-lasting presence on the Tibetan
Plateau which is known as the highest plateau in the world, may offer a unique opportunity to …

[PDF][PDF] Genomic dissection of population substructure of Han Chinese and its implication in association studies

…, Y Yang, Y Wang, W Fu, Y An, J Wang, J Tan… - The American Journal of …, 2009 - cell.com
To date, most genome-wide association studies (GWAS) and studies of fine-scale population
structure have been conducted primarily on Europeans. Han Chinese, the largest ethnic …

[HTML][HTML] Modeling recent human evolution in mice by expression of a selected EDAR variant

…, S Wang, J Tan, P Gerbault, A Wark, L Tan… - Cell, 2013 - cell.com
An adaptive variant of the human Ectodysplasin receptor, EDARV370A, is one of the
strongest candidates of recent positive selection from genome-wide scans. We have modeled …

Epidemiological evidence that indoor air pollution from cooking with solid fuels accelerates skin aging in Chinese women

…, B Deng, C Ma, A Ren, J Zhang, J Tan… - Journal of …, 2015 - Elsevier
Background Recently, we showed that outdoor air pollution exposure from traffic and industry
is associated with an increased risk of skin aging in Caucasian women. In China, indoor …

[PDF][PDF] Limb development genes underlie variation in human fingerprint patterns

J Li, JD Glover, H Zhang, M Peng, J Tan, CB Mallick… - Cell, 2022 - cell.com
Fingerprints are of long-standing practical and cultural interest, but little is known about the
mechanisms that underlie their variation. Using genome-wide scans in Han Chinese cohorts, …

Genetic variants underlying differences in facial morphology in East Asian and European populations

…, S Wu, S Du, W Qian, J Chen, L Qiao, Y Yang, J Tan… - Nature Genetics, 2022 - nature.com
Facial morphology—a conspicuous feature of human appearance—is highly heritable.
Previous studies on the genetic basis of facial morphology were performed mainly in European-…

The adaptive variant EDARV370A is associated with straight hair in East Asians

J Tan, Y Yang, K Tang, PC Sabeti, L Jin, S Wang - Human genetics, 2013 - Springer
Hair straightness/curliness is a highly heritable trait amongst human populations. Previous
studies have reported European specific genetic variants influencing hair straightness, but …

[HTML][HTML] Detecting genetic association of common human facial morphological variation using high density 3D image registration

S Peng, J Tan, S Hu, H Zhou, J Guo… - PLoS computational …, 2013 - journals.plos.org
Human facial morphology is a combination of many complex traits. Little is known about the
genetic basis of common facial morphological variation. Existing association studies have …

[HTML][HTML] Genome-wide variants of Eurasian facial shape differentiation and a prospective model of DNA based face prediction

…, Y Yang, P Fu, S Hu, H Zhou, S Peng, J Tan… - Journal of Genetics and …, 2018 - Elsevier
It is a long-standing question as to which genes define the characteristic facial features among
different ethnic groups. In this study, we use Uyghurs, an ancient admixed population to …