Acetylcarnitine is a candidate diagnostic and prognostic biomarker of hepatocellular carcinoma

…, K Yu, Q Ling, Q Cheng, S Chen, M Zhu, J Fang… - Cancer research, 2016 - AACR
The identification of serum biomarkers to improve the diagnosis and prognosis of
hepatocellular carcinoma has been elusive to date. In this study, we took a mass spectroscopic …

[HTML][HTML] Serum metabolomics reveals serotonin as a predictor of severe dengue in the early phase of dengue fever

L Cui, YH Lee, TL Thein, J Fang, J Pang… - PLoS neglected …, 2016 - journals.plos.org
Effective triage of dengue patients early in the disease course for in- or out-patient management
would be useful for optimal healthcare resource utilization while minimizing poor clinical …

[HTML][HTML] Limited value of pro-inflammatory oxylipins and cytokines as circulating biomarkers in endometriosis–a targeted 'omics study

YH Lee, L Cui, J Fang, BSM Chern, HH Tan… - Scientific reports, 2016 - nature.com
Endometriosis is a common, complex gynecologic disorder characterized by the presence
of endometrial-like tissues at extrauterine sites. Elevation in protein and lipid mediators of …

[HTML][HTML] Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study [S]

…, WP Koh, JM Yuan, JW Newman, J Su, J Fang… - Journal of lipid …, 2016 - ASBMB
We aimed to examine the prospective association between plasma FAs, oxylipins, and risk
of acute myocardial infarction (AMI) in a Singapore Chinese population. A nested case-…

Serum metabolomics investigation of humanized mouse model of dengue virus infection

L Cui, J Hou, J Fang, YH Lee, VV Costa… - Journal of …, 2017 - Am Soc Microbiol
Dengue is an acute febrile illness caused by dengue virus (DENV) and a major cause of
morbidity and mortality in tropical and subtropical regions of the world. The lack of an …

[HTML][HTML] Exometabolomic analysis of decidualizing human endometrial stromal and perivascular cells

…, ES Lucas, L Cui, K Murakami, J Fang… - Frontiers in Cell and …, 2021 - frontiersin.org
Differentiation of endometrial fibroblasts into specialized decidual cells controls embryo
implantation and transforms the cycling endometrium into a semi-permanent, immune-protective …

Serial metabolome changes in a prospective cohort of subjects with influenza viral infection and comparison with dengue fever

L Cui, J Fang, EE Ooi, YH Lee - Journal of Proteome Research, 2017 - ACS Publications
Influenza virus infection (IVI) and dengue virus infection (DVI) are major public health threats.
Between IVI and DVI, clinical symptoms can be overlapping yet infection-specific, but host …

Omega-6-derived oxylipin changes in serum of patients with hepatitis B virus-related liver diseases

Y Lu, J Fang, L Zou, L Cui, X Liang, SG Lim, YY Dan… - Metabolomics, 2018 - Springer
… , precision, recovery, and stability as the previous published reports (Fang et al. 2017; Lu et
al. 2017), … Jinling Fang … Yonghai Lu and Jinling Fang have contributed equally to this work. …

Overexpression of CD86 enhances the ability of THP‐1 macrophages to defend against Talaromyces marneffei

R Chen, D Yang, L Shen, J Fang… - Immunity, inflammation …, 2022 - Wiley Online Library
Background Macrophages are the first line of defense against Talaromyces marneffei. CD86
is a surface molecule expressed on antigen‐presenting cells, such as macrophages, that …

Targeted metabolomics reveals altered oxylipin profiles in plasma of mild cognitive impairment patients

J Fang, L Cui, Y Sun, L Feng, CN Ong - Metabolomics, 2017 - Springer
Introduction and objective Mild cognitive impairment (MCI) is considered to be a prodromal
stage of Alzheimer’s disease (AD), which is the most common type of dementia. Although …