Background More than 1000 reports have been published in the past two decades on
associations between variants in candidate genes and risk of breast cancer. Results have been …

We assembled an ancestrally diverse collection of genome-wide association studies (GWAS)
of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non…

Stratification of women according to their risk of breast cancer based on polygenic risk scores
(PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, …

We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes (T2D)
in east Asian populations. We followed our stage 1 meta-analysis of eight T2D genome-…

We carried out a genome-wide association study among Chinese women to identify risk
variants for breast cancer. After analyzing 607,728 SNPs in 1,505 cases and 1,522 controls, we …

Estrogen receptor (ER)-negative tumors represent 20–30% of all breast cancers, with a higher
proportion occurring in younger women and women of African ancestry 1 . The etiology 2 …

Multiple genetic loci associated with obesity or body mass index (BMI) have been identified
through genome-wide association studies conducted predominantly in populations of …

Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health.
To date, most genetic studies of glycemic traits have focused on individuals of European …

Meta-analyses of genome-wide association studies (GWAS) have identified more than 240
loci that are associated with type 2 diabetes (T2D) 1 , 2 ; however, most of these loci have …

Colorectal cancer (CRC) is a leading cause of mortality worldwide. We conducted a genome-wide
association study meta-analysis of 100,204 CRC cases and 154,587 controls of …