Microglia are the primary immune cells in the brain. Under physiological conditions, they
typically stay in a "resting" state, with ramified processes continuously extending to and …

Vascular integrity helps maintain brain microenvironment homeostasis, which is critical for
the normal development and function of the central nervous system. It is known that neural …

The China Brain Project covers both basic research on neural mechanisms underlying
cognition and translational research for the diagnosis and intervention of brain diseases as well …

The brain blood vasculature consists of a highly ramified vessel network that is tailored to meet
its physiological functions. How the brain vasculature is formed has long been fascinating …

Animals carrying exogenous genes integrated at specific genomic loci are versatile tools for
biological research [1]. Zebrafish (Danio rerio), an emerging vertebrate animal model, is …

PRKAG2 cardiac syndrome is an autosomal dominant inherited disease resulted from mutations
in the PRKAG2 gene that encodes γ2 regulatory subunit of AMP-activated protein kinase…

Visual cues often modulate auditory signal processing, leading to improved sound detection.
However, the synaptic and circuit mechanism underlying this cross-modal modulation …

Rationale: Wiring vascular and neural networks are known to share common molecular
signaling pathways. Activation of transient receptor potential type C channels (TRPCs) has …

In cultures of hippocampal neurons, induction of long-term synaptic potentiation or depression
by repetitive synaptic activity is accompanied by a retrograde spread of potentiation or …

Habenula (Hb) plays critical roles in emotion-related behaviors through integrating inputs
mainly from the limbic system and basal ganglia. However, Hb also receives inputs from …