User profiles for João Paulo Cavalcanti-de-Albuquerque

Joao Paulo Cavalcanti de Albuquerque

Research Associate, University of Manchester
Verified email at manchester.ac.uk
Cited by 426

[HTML][HTML] Regulation of substrate utilization and adiposity by Agrp neurons

JP Cavalcanti-de-Albuquerque, J Bober… - Nature …, 2019 - nature.com
The type of nutrient utilized by the organism at any given time—substrate utilization—is a
critical component of energy metabolism. The neuronal mechanisms involved in the regulation …

Physical exercise improves mitochondrial function in ovariectomized rats

…, JP Cavalcanti-de-Albuquerque - Journal of …, 2022 - joe.bioscientifica.com
Estrogen deficiency causes metabolic disorders in humans and rodents, including in part
due to changes in energy expenditure. We have shown previously that skeletal muscle …

Coupling of GABA metabolism to mitochondrial glucose phosphorylation

JP Cavalcanti-de-Albuquerque… - Neurochemical …, 2021 - Springer
Glucose and oxygen (O 2 ) are vital to the brain. Glucose metabolism and mitochondria play
a pivotal role in this process, culminating in the increase of reactive O 2 species. …

[HTML][HTML] Isolation of mitochondria from fresh mice lung tissue

…, DF Oliveira, JP Cavalcanti-de-Albuquerque… - Frontiers in …, 2021 - frontiersin.org
Direct analysis of isolated mitochondria enables a better understanding of lung dysfunction.
Despite well-defined mitochondrial isolation protocols applicable to other tissues, such as …

Rolling out physical exercise and energy homeostasis: focus on hypothalamic circuitries

JP Cavalcanti-de-Albuquerque, J Donato Jr - Frontiers in …, 2021 - Elsevier
Energy balance is the fine regulation of energy expenditure and energy intake. Negative
energy balance causes body weight loss, while positive energy balance promotes weight gain. …

[PDF][PDF] Hypothalamic AgRP neurons exert top-down control on systemic TNF-α release during endotoxemia

…, E Harno, J Hunter, JP Cavalcanti-de-Albuquerque… - Current Biology, 2022 - cell.com
Loss of appetite and negative energy balance are common features of endotoxemia in all
animals and are thought to have protective roles by reducing nutrient availability to host and …

Mitochondria-Bound Hexokinase (mt-HK) Activity Differ in Cortical and Hypothalamic Synaptosomes: Differential Role of mt-HK in H2O2 Depuration

JP Cavalcanti-de-Albuquerque… - Molecular …, 2018 - Springer
Glucose and oxygen are vital for the brain, as these molecules provide energy and metabolic
intermediates that are necessary for cell function. The glycolysis pathway and mitochondria …

Rapid shift in substrate utilization driven by hypothalamic Agrp neurons

JP Cavalcanti-de-Albuquerque, MR Zimmer, J Bober… - BioRxiv, 2016 - biorxiv.org
Agrp neurons drive feeding. To what extend these neurons participate in the regulation of
other homeostatic processes is not well understood. We investigated the role of Agrp neurons …

Intense physical exercise potentiates glucose inhibitory effect over food intake of male Wistar rats

JP CavalcantideAlbuquerque… - Experimental …, 2018 - Wiley Online Library
… In a treadmill for rats (AVS project, São Paulo, Brazil), the rats were motivated to run by electric
shock (Cavalcanti-de-Albuquerque et al., 2014). An acclimatization period was conducted …

Regulation of substrate utilization and adiposity by Agrp neurons

JPC de-Albuquerque, J Bober… - Nature …, 2019 - econpapers.repec.org
The type of nutrient utilized by the organism at any given time—substrate utilization—is a
critical component of energy metabolism. The neuronal mechanisms involved in the regulation …