Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
…, T Saito, S Narushima, K Hase, S Kim, JV Fritz… - Nature, 2013 - nature.com
Manipulation of the gut microbiota holds great promise for the treatment of inflammatory and
allergic diseases 1 , 2 . Although numerous probiotic microorganisms have been identified 3 …
allergic diseases 1 , 2 . Although numerous probiotic microorganisms have been identified 3 …
[HTML][HTML] A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
Abstract Changes in the human gastrointestinal microbiome are associated with several
diseases. To infer causality, experiments in representative models are essential, but widely …
diseases. To infer causality, experiments in representative models are essential, but widely …
[HTML][HTML] Birth mode is associated with earliest strain-conferred gut microbiome functions and immunostimulatory potential
L Wampach, A Heintz-Buschart, JV Fritz… - Nature …, 2018 - nature.com
The rate of caesarean section delivery (CSD) is increasing worldwide. It remains unclear
whether disruption of mother-to-neonate transmission of microbiota through CSD occurs and …
whether disruption of mother-to-neonate transmission of microbiota through CSD occurs and …
[HTML][HTML] From meta-omics to causality: experimental models for human microbiome research
Large-scale ‘meta-omic’ projects are greatly advancing our knowledge of the human
microbiome and its specific role in governing health and disease states. A myriad of ongoing …
microbiome and its specific role in governing health and disease states. A myriad of ongoing …
The extracellular RNA complement of Escherichia coli
A Ghosal, BB Upadhyaya, JV Fritz… - …, 2015 - Wiley Online Library
The secretion of biomolecules into the extracellular milieu is a common and well‐conserved
phenomenon in biology. In bacteria, secreted biomolecules are not only involved in intra‐…
phenomenon in biology. In bacteria, secreted biomolecules are not only involved in intra‐…
Sources and functions of extracellular small RNAs in human circulation
JV Fritz, A Heintz-Buschart, A Ghosal… - Annual review of …, 2016 - annualreviews.org
Various biotypes of endogenous small RNAs (sRNAs) have been detected in human
circulation, including microRNAs, transfer RNAs, ribosomal RNA, and yRNA fragments. These …
circulation, including microRNAs, transfer RNAs, ribosomal RNA, and yRNA fragments. These …
Prevalence of SARS-CoV-2 infection in the Luxembourgish population–the CON-VINCE study
BACKGROUND The World Health Organization declared the outbreak of coronavirus disease
to be a public health emergency of international concern on January 30, 2020. The first …
to be a public health emergency of international concern on January 30, 2020. The first …
[HTML][HTML] Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in …
Immunoresponsive gene 1 (IRG1) is one of the highest induced genes in macrophages under
pro-inflammatory conditions. Its function has been recently described: it codes for immune-…
pro-inflammatory conditions. Its function has been recently described: it codes for immune-…
HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction
S Schmidt, JV Fritz, J Bitzegeio, OT Fackler, OT Keppler - MBio, 2011 - Am Soc Microbiol
The intrinsic immunity factor CD317 (BST-2/HM1.24/tetherin) imposes a barrier to HIV-1
release at the cell surface that can be overcome by the viral protein Vpu. Expression of Vpu …
release at the cell surface that can be overcome by the viral protein Vpu. Expression of Vpu …
[HTML][HTML] Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein
…, M Peeters, GH Learn, F Bibollet-Ruche, JV Fritz… - PLoS …, 2012 - journals.plos.org
HIV-1 groups M and N emerged within the last century following two independent cross-species
transmissions of SIVcpz from chimpanzees to humans. In contrast to pandemic group M …
transmissions of SIVcpz from chimpanzees to humans. In contrast to pandemic group M …