CD8 + T cells infiltrating tumors are largely dysfunctional, but whether a subset maintains
superior functionality remains ill defined. By high-dimensional single cell analysis of millions of …

Development of higher rates of nondiabetic glomerulosclerosis (GS) in African Americans has
been attributed to two coding sequence variants (G1 and G2) in the APOL1 gene. To date, …

The liver is considered a preferential tissue for NK cells residency. In humans, almost 50%
of all intrahepatic lymphocytes are NK cells that are strongly imprinted in a liver-specific …

Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Natural killer (NK) cells are important effectors of innate immunity playing a key role in the
eradication and clearance of viral infections. Over the recent years, several studies have …

Natural Killer (NK) cells are innate lymphocytes playing pivotal roles in host defense and
immune-surveillance. The homeostatic modulation of germ-line encoded/non-rearranged …

γδ T cells account for a large fraction of human intestinal intraepithelial lymphocytes (IELs)
endowed with potent antitumor activities. However, little is known about their origin, phenotype…

Natural cytotoxicity receptors (NCRs) were originally identified as specific natural killer cell
activating receptors that, on binding to their endogenous ligands, trigger the killing of tumor …

Natural Killer (NK) cells are innate lymphocytes able to mediate immune-surveillance and
clearance of viral infected and tumor-transformed cells. Growing experimental and clinical …

Human Vδ2 cells are innate-like γδ T effectors performing potent immune surveillance against
tumors. The constitutive expression of NKG2A identifies a subset of Vδ2 T cells licensed …