Molecular recognition at the protein-hydroxyapatite interface

…, GP Drobny, WJ Shaw, JR Long… - Critical Reviews in …, 2003 - journals.sagepub.com
Proteins found in mineralized tissues act as nature’s crystal engineers, where they play a
key role in promoting or inhibiting the growth of minerals such as hydroxyapatite (bones/teeth) …

Toward 20 T magnetic resonance for human brain studies: opportunities for discovery and neuroscience rationale

TF Budinger, MD Bird, L Frydman, JR Long… - … Resonance Materials in …, 2016 - Springer
An initiative to design and build magnetic resonance imaging (MRI) and spectroscopy (MRS)
instruments at 14 T and beyond to 20 T has been underway since 2012. This initiative has …

Structure and dynamics of hydrated statherin on hydroxyapatite as determined by solid-state NMR

JR Long, WJ Shaw, PS Stayton, GP Drobny - Biochemistry, 2001 - ACS Publications
Proteins directly control the nucleation and growth of biominerals, but the details of molecular
recognition at the protein−biomineral interface remain poorly understood. The elucidation …

The structure, dynamics, and energetics of protein adsorption—lessons learned from adsorption of statherin to hydroxyapatite

…, WJ Shaw, JM Gibson, JR Long… - Magnetic …, 2007 - Wiley Online Library
Proteins are found to be involved in interaction with solid surfaces in numerous natural
events. Acidic proteins that adsorb to crystal faces of a biomineral to control the growth and …

[HTML][HTML] Chimeric peptides of statherin and osteopontin that bind hydroxyapatite and mediate cell adhesion

M Gilbert, WJ Shaw, JR Long, K Nelson… - Journal of Biological …, 2000 - ASBMB
Extracellular matrix proteins play key roles in controlling the activities of osteoblasts and
osteoclasts in bone remodeling. These bone-specific extracellular matrix proteins contain amino …

Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites

…, Y Li, CYE Lin, JK Liou, JF Lirng, F Liu, JR Long, R Ma… - Neuroimage, 2019 - Elsevier
Accurate and reliable quantification of brain metabolites measured in vivo using 1 H magnetic
resonance spectroscopy (MRS) is a topic of continued interest. Aside from differences in …

A method for dynamic nuclear polarization enhancement of membrane proteins

…, MA Caporini, GE Fanucci, JR Long - Angewandte …, 2015 - Wiley Online Library
Dynamic nuclear polarization (DNP) magic‐angle spinning (MAS) solid‐state NMR (ssNMR)
spectroscopy has the potential to enhance NMR signals by orders of magnitude and to …

Functional amyloids in Streptococcus mutans, their use as targets of biofilm inhibition and initial characterization of SMU_63c

…, DB Senadheera, DG Cvitkovitch, JR Long… - …, 2017 - microbiologyresearch.org
Amyloids have been identified as functional components of the extracellular matrix of bacterial
biofilms. Streptococcus mutans is an established aetiologic agent of dental caries and a …

A peptide that inhibits hydroxyapatite growth is in an extended conformation on the crystal surface

JR Long, JL Dindot, H Zebroski… - Proceedings of the …, 1998 - National Acad Sciences
Proteins play an important role in the biological mechanisms controlling hard tissue
development, but the details of molecular recognition at inorganic crystal interfaces remain poorly …

Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase α-aminoacrylate intermediate

…, CA Chang, JR Long… - Proceedings of the …, 2022 - National Acad Sciences
NMR-assisted crystallography—the integrated application of solid-state NMR, X-ray
crystallography, and first-principles computational chemistry—holds significant promise for …