The removal of non-brain signal from magnetic resonance imaging (MRI) data, known as
skull-stripping, is an integral component of many neuroimage analysis streams. Despite their …

The absolute requirement for reproduction implies that the hypothalamo-pituitary-gonadal
axis, controlling fertility, is an evolutionary robust mechanism. The GnRH neurons of the …

The postnatal mouse ovary is rich in quiescent and early-growing oocytes, each one surrounded
by a layer of somatic granulosa cells (GCs) on a basal lamina. As oocytes start to grow …

In the ovary, initiation of follicle growth is marked by cuboidalization of flattened granulosa
cells (GCs). The regulation and cell biology of this shape change remains poorly understood. …

Staphylococcus aureus bloodstream (SAB) infection is a common and severe infectious
disease, with a 90-day mortality of 15%–30%. Despite this, <3000 people have been …

Brain cells are arranged in laminar, nuclear, or columnar structures, spanning a range of
scales. Here, we construct a reliable cell census in the frontal lobe of human cerebral cortex at …

Androgens are essential for the normal function of mature antral follicles but also have a
role in the early stages of follicle development. Polycystic ovary syndrome (PCOS), the most …

Background Nafamostat mesylate is a potent in vitro antiviral agent that inhibits the host
transmembrane protease serine 2 enzyme used by severe acute respiratory syndrome …

Background Optimal thromboprophylaxis for hospitalized patients with coronavirus disease
2019 (Covid-19) is uncertain. Methods In an open-label, adaptive platform trial, we randomly …

Bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) are 2
closely related TGF-β ligands implicated as key regulators of follicle development and fertility. …