[PDF][PDF] Primary cilia mediate diverse kinase inhibitor resistance mechanisms in cancer
Primary cilia are microtubule-based organelles that detect mechanical and chemical stimuli.
Although cilia house a number of oncogenic molecules (including Smoothened, KRAS, …
Although cilia house a number of oncogenic molecules (including Smoothened, KRAS, …
[PDF][PDF] Dual targeting of PDGFRα and FGFR1 displays synergistic efficacy in malignant rhabdoid tumors
JP Wong, JR Todd, MA Finetti, F McCarthy, M Broncel… - Cell reports, 2016 - cell.com
Subunits of the SWI/SNF chromatin remodeling complex are mutated in a significant
proportion of human cancers. Malignant rhabdoid tumors (MRTs) are lethal pediatric cancers …
proportion of human cancers. Malignant rhabdoid tumors (MRTs) are lethal pediatric cancers …
[HTML][HTML] Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer
JR Todd, KA Ryall, S Vyse, JP Wong, RC Natrajan… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Tumour cell-extracellular matrix (ECM) interactions are fundamental for discrete steps in
breast cancer progression. In particular, cancer cell adhesion to ECM proteins present in the …
breast cancer progression. In particular, cancer cell adhesion to ECM proteins present in the …
[HTML][HTML] Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib
S Vyse, F McCarthy, M Broncel, A Paul, JP Wong… - Journal of …, 2018 - Elsevier
Acquired drug resistance impacts the majority of patients being treated with tyrosine kinase
inhibitors (TKIs) and remains a key challenge in modern anti-cancer therapy. The lack of …
inhibitors (TKIs) and remains a key challenge in modern anti-cancer therapy. The lack of …
AT-20 INTEGRATED PATHWAY ANALYSIS OF RHABDOID TUMOR SUBTYPES IDENTIFIES KEY SMARCB1-DEPENDENCIES AND THERAPEUTIC …
MA Finetti, A Del Carpio-Pons, JP Wong… - Neuro …, 2016 - academic.oup.com
BACKGROUND: Despite multiparametric MRI, uncertainty remains in the radiological
phenotyping of intracranial tumours and their specific molecular subtype. We introduce a …
phenotyping of intracranial tumours and their specific molecular subtype. We introduce a …
Analysis of buccolingual dimensional changes of the extraction socket using the" ice cream cone" flapless grafting technique.
JH P Tan-Chu, FJ Tuminelli, KS Kurtz… - … of Periodontics & …, 2014 - search.ebscohost.com
The socket or ridge preservation approach known as the" ice cream cone" technique was
used in type 2 sockets in this retrospective analysis of 11 extraction sites. A type 2 extraction …
used in type 2 sockets in this retrospective analysis of 11 extraction sites. A type 2 extraction …
In vitro methods for studying the mechanisms of resistance to DNA-damaging therapeutic drugs
P Khongkow, AW Middleton, JPM Wong… - Cancer Drug Resistance …, 2016 - Springer
Most commonly used anticancer drugs exert their effects mainly by causing DNA damage.
The enhancement in DNA damage response (DDR) is considered a key mechanism that …
The enhancement in DNA damage response (DDR) is considered a key mechanism that …
[HTML][HTML] Chemistry of buttermilk solid antioxidant activity
PYY Wong, DD Kitts - Journal of dairy science, 2003 - Elsevier
Antioxidant activity of buttermilk solids was assessed by analyzing for relative reducing
activity, sulfhydryl content, and ferrous and ferric iron binding affinity. These experiments were …
activity, sulfhydryl content, and ferrous and ferric iron binding affinity. These experiments were …
[HTML][HTML] Diagnosis and management of headaches in the Emergency Department (ED) in adults and children
YJ Zhao, JYX Lim, PS Wong - Neurology India, 2021 - journals.lww.com
Background: Headache accounts for a significant number of cases presenting to the Emergency
Department (ED) and has a high societal cost, contributed by recurrent ED and clinic …
Department (ED) and has a high societal cost, contributed by recurrent ED and clinic …
[HTML][HTML] Quantification and Analysis of Micro-Level Activities Data from Children Aged 1–12 Years Old for Use in the Assessments of Exposure to Recycled Tire on Turf …
N Lopez-Galvez, J Claude, P Wong… - International Journal of …, 2022 - mdpi.com
Background: There are growing health concerns about exposure to toxicants released from
recycled tire rubber, which is commonly used in synthetic turf and playground mats. To better …
recycled tire rubber, which is commonly used in synthetic turf and playground mats. To better …