[HTML][HTML] Functional tradeoffs underpin salinity-driven divergence in microbial community composition

…, K Ininbergs, J Goll, J Asplund-Samuelsson… - PloS one, 2014 - journals.plos.org
Bacterial community composition and functional potential change subtly across gradients in
the surface ocean. In contrast, while there are significant phylogenetic divergences between …

[HTML][HTML] Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes

…, SM Björk, J Asplund-Samuelsson… - Nature …, 2020 - nature.com
Cyanobacteria are model organisms for photosynthesis and are attractive for biotechnology
applications. To aid investigation of genotype-phenotype relationships in cyanobacteria, we …

Protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator

…, A Mattausch, Q Chen, J Asplund-Samuelsson… - Elife, 2021 - elifesciences.org
Bacteria must balance the different needs for substrate assimilation, growth functions, and
resilience in order to thrive in their environment. Of all cellular macromolecules, the bacterial …

Kinetic modeling of the Calvin cycle identifies flux control and stable metabolomes in Synechocystis carbon fixation

M Janasch, J Asplund-Samuelsson… - Journal of …, 2019 - academic.oup.com
Biological fixation of atmospheric CO 2 via the Calvin–Benson–Bassham cycle has massive
ecological impact and offers potential for industrial exploitation, either by improving carbon …

[HTML][HTML] Prokaryotic caspase homologs: phylogenetic patterns and functional characteristics reveal considerable diversity

J Asplund-Samuelsson, B Bergman, J Larsson - PLoS One, 2012 - journals.plos.org
Caspases accomplish initiation and execution of apoptosis, a programmed cell death
process specific to metazoans. The existence of prokaryotic caspase homologs, termed …

[HTML][HTML] Thermodynamic analysis of computed pathways integrated into the metabolic networks of E. coli and Synechocystis reveals contrasting expansion potential

J Asplund-Samuelsson, M Janasch, EP Hudson - Metabolic engineering, 2018 - Elsevier
Introducing biosynthetic pathways into an organism is both reliant on and challenged by
endogenous biochemistry. Here we compared the expansion potential of the metabolic network …

[HTML][HTML] Dissection of microbial community functions during a cyanobacterial bloom in the Baltic Sea via metatranscriptomics

C Berg, CL Dupont, J Asplund-Samuelsson… - Frontiers in Marine …, 2018 - frontiersin.org
Marine and brackish surface waters are highly dynamic habitats that undergo repeated
seasonal variations in microbial community composition and function throughout time. While …

[HTML][HTML] Thermodynamic limitations of PHB production from formate and fructose in Cupriavidus necator

M Janasch, N Crang, J Asplund-Samuelsson… - Metabolic …, 2022 - Elsevier
The chemolithotroph Cupriavidus necator H16 is known as a natural producer of the
bioplastic-polymer PHB, as well as for its metabolic versatility to utilize different substrates, including …

[HTML][HTML] Diversity and expression of bacterial metacaspases in an aquatic ecosystem

J Asplund-Samuelsson, J Sundh, CL Dupont… - Frontiers in …, 2016 - frontiersin.org
Metacaspases are distant homologs of metazoan caspase proteases, implicated in stress
response, and programmed cell death (PCD) in bacteria and phytoplankton. While the few …

[HTML][HTML] Wide range of metabolic adaptations to the acquisition of the Calvin cycle revealed by comparison of microbial genomes

J Asplund-Samuelsson, EP Hudson - PLOS Computational …, 2021 - journals.plos.org
Knowledge of the genetic basis for autotrophic metabolism is valuable since it relates to both
the emergence of life and to the metabolic engineering challenge of incorporating CO 2 as …