A splitCas9 phenotypic screen in Toxoplasma gondii identifies proteins involved in host cell egress and invasion

W Li, J Grech, JF Stortz, M Gow, J Periz… - Nature …, 2022 - nature.com
Apicomplexan parasites, such as Toxoplasma gondii, have specific adaptations that enable
invasion and exit from the host cell. Owing to the phylogenetic distance between …

Formin-2 drives polymerisation of actin filaments enabling segregation of apicoplasts and cytokinesis in Plasmodium falciparum

JF Stortz, M Del Rosario, M Singer, JM Wilkes… - Elife, 2019 - elifesciences.org
10.7554/eLife.49030.001 In addition to its role in erythrocyte invasion, Plasmodium
falciparum actin is implicated in endocytosis, cytokinesis and inheritance of the chloroplast-like …

Apicomplexan F‐actin is required for efficient nuclear entry during host cell invasion

…, F Latorre‐Barragan, S Das, GS Pall, JF Stortz… - EMBO …, 2019 - embopress.org
The obligate intracellular parasites Toxoplasma gondii and Plasmodium spp. invade host
cells by injecting a protein complex into the membrane of the targeted cell that bridges the two …

The multiple functions of actin in apicomplexan parasites

S Das, JF Stortz, M Meissner, J Periz - Cellular Microbiology, 2021 - Wiley Online Library
The cytoskeletal protein actin is highly abundant and conserved in eukaryotic cells. It occurs
in two different states‐ the globular (G‐actin) form, which can polymerise into the …

A phenotypic screen using splitCas9 identifies essential genes required for actin regulation during host cell egress and invasion by Toxoplasma gondii

W Li, J Grech, JF Stortz, M Gow, J Periz, M Meissner… - BioRxiv, 2021 - biorxiv.org
Apicomplexan parasites, such as Toxoplasma gondii, possess unique organelles,
cytoskeletal structures, signalling cascades, replicate by internal budding within a specialised …

Formin-2 drives intracellular polymerisation of actin filaments enabling correct segregation of apicoplasts in Plasmodium falciparum and Toxoplasma gondii

JF Stortz, M Singer, JM Wilkes, M Meissner, S Das - bioRxiv, 2018 - biorxiv.org
Pathogenic obligate-intracellular apicomplexan parasites possess an essential chloroplast-like
organelle called the apicoplast that undergoes division and segregation during …

A conditional CRISPR/Cas9 system gives novel insights into actin dynamics in Toxoplasma gondii

JF Stortz - 2020 - theses.gla.ac.uk
… I, Johannes Felix Stortz hereby declare that I am the sole author of this thesis and performed
all of the work presented, with the following exceptions highlighted below. No part of this …

[HTML][HTML] Review of stationary energy storage systems applications, their placement, and techno-economic potential

J Wüllner, N Reiners, L Millet, M Salibi, F Stortz… - Current Sustainable …, 2021 - Springer
Purpose of Review This review paper attempts to give a general overview on the BESS
applications that demonstrate a high potential in the past few years, identifying most relevant …

Development and Analysis of an Off-grid Solar Food Processing System in Kenya

…, DM Subasi, N Pfanner, N Reiners, F Stortz… - 2022 - publica.fraunhofer.de
The agricultural sector, including fisheries, is one of the main economic drivers in Kenya, which
employs two million people to accelerate the rural community development in the country…

Toxoplasma Gondii Tubulin Cofactor B Plays a Key Role in Host Cell Invasion and Replication

SNF da Conceição Francisco - 2020 - search.proquest.com
Tubulin cofactors participate in the folding, dimerization, and dissociation pathways of the
tubulin dimer, being implicated in the control of tubulin proteostasis and consequently in the …