[HTML][HTML] Hypoxia-induced downregulation of microRNA-186-5p in endothelial cells promotes non-small cell lung cancer angiogenesis by upregulating protein kinase …

…, AS Boewe, E Ampofo, E Ebert, J Hohneck… - … Therapy-Nucleic Acids, 2023 - cell.com
The tumor microenvironment stimulates the angiogenic activity of endothelial cells (ECs) to
facilitate tumor vascularization, growth, and metastasis. The involvement of microRNA-186-…

[HTML][HTML] SCARA5 Is Overexpressed in Prostate Cancer and Linked to Poor Prognosis

FA Flockerzi, J Hohneck, M Saar, RM Bohle, PR Stahl - Diagnostics, 2023 - mdpi.com
Prostate cancer is one of the most common malignancies worldwide, showing a wide range
of clinical behaviors. Therefore, several treatment options arise out of the diagnosis “prostate …

[HTML][HTML] Suppression of endothelial miR-22 mediates non-small cell lung cancer cell-induced angiogenesis

…, C Körbel, E Ampofo, E Ebert, J Hohneck… - … Therapy-Nucleic Acids, 2021 - cell.com
MicroRNAs (miRNAs) expressed in endothelial cells (ECs) are powerful regulators of
angiogenesis, which is essential for tumor growth and metastasis. Here, we demonstrated that miR-…

[HTML][HTML] THSD7A Positivity Is Associated with High Expression of FAK in Prostate Cancer

FA Flockerzi, J Hohneck, M Saar, RM Bohle, PR Stahl - Diagnostics, 2023 - mdpi.com
Prostate cancer is one of the most common malignancies, and there are a wide range of
treatment options after diagnosis. Most prostate cancers behave in an indolent manner. …

TRPC6 is altered in COVID-19 pneumonia

G Leidinger, F Flockerzi, J Hohneck, RM Bohle… - Chemico-Biological …, 2022 - Elsevier
In this Letter to the Editor supportive data were presented to a recent paper published in this
journal reporting the involvement of TRP channels in COVID-19 pneumonia and its role for …

[HTML][HTML] THSD7A Positivity Predicts Poor Survival and Is Linked to High FAK Expression and FGFR1-Wildtype in Female Patients with Squamous Cell Carcinoma of …

FA Flockerzi, J Hohneck, F Langer, RM Bohle… - International Journal of …, 2023 - mdpi.com
Lung cancer is the leading cause of cancer-related deaths in the western world, with
squamous cell carcinoma being one of the most common histological subtypes. Prognostic and …

MicroRNA-Expression von primären Plattenepithelkarzinomen der Lunge in Abhängigkeit vom histologischen Grading

JE Hohneck - 2023 - publikationen.sulb.uni-saarland.de
Hintergründe: MicroRNAs sind einsträngige, kurze, nicht (für ein Protein) kodierende
Ribonukleinsäuren, welche die Proteintranslation regulieren. Sie sind dadurch in der Lage in eine …

[HTML][HTML] Stromal-epithelial interaction induces GALNT14 in prostate carcinoma cells

ED Czyrnik, M Wiesehöfer, JT Dankert, S Wach… - Frontiers in …, 2023 - frontiersin.org
Introduction Cell-cell communication is an important process in healthy tissue but also gains
enhanced attention regarding pathological tissue. To date, the tumor microenvironment is …

xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023. 1-miR-26a/30d/30e axis

ED Wilhelm, M Wiesehöfer, JT Dankert, S Wach… - 2023 - researchsquare.com
Purpose Prostate cancer is the second most common type of cancer in male worldwide.
Stromal-epithelial interaction is thought to have a major impact on cancer development and …

Diagnosis and Outcome of Patients with Idiopathic Hypereosinophilic Syndrome and Cardiac Involvement

J Lübke, A Hohneck, J Leipe, N Naumann, A Fabarius… - Blood, 2023 - Elsevier
Introduction: Diagnostic criteria of idiopathic hypereosinophilic syndrome (iHES) comprise
persisting reactive/non-clonal eosinophilia ≥1.5 G/l and associated organ infiltration/…