Identification of loci associated with schizophrenia by genome-wide association and follow-up

…, W Maier, M Rietschel, S Zammit, J Schumacher… - Nature …, 2008 - nature.com
We carried out a genome-wide association study of schizophrenia (479 cases, 2,937 controls)
and tested loci with P < 10 −5 in up to 16,726 additional subjects. Of 12 loci followed up, 3 …

Complementarity modeling of hybrid systems

…, JM Schumacher - IEEE Transactions on …, 1998 - ieeexplore.ieee.org
A complementarity framework is described for the modeling of certain classes of mixed
continuous/discrete dynamical systems. The use of such a framework is well known for …

[PDF][PDF] Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder

…, J Lönnqvist, MM Nöthen, J Schumacher… - The American Journal of …, 2003 - cell.com
Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage.
The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD …

Linear complementarity systems

W Heemels, JM Schumacher, S Weiland - SIAM journal on applied …, 2000 - SIAM
We introduce a new class of dynamical systems called "linear complementarity systems."
The time evolution of these systems consists of a series of continuous phases separated by "…

[HTML][HTML] Genome-wide association study reveals two new risk loci for bipolar disorder

…, M Mattheisen, AJ Forstner, J Schumacher… - Nature …, 2014 - nature.com
Bipolar disorder (BD) is a common and highly heritable mental illness and genome-wide
association studies (GWAS) have robustly identified the first common genetic variants involved …

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression

J Schumacher, R Abou Jamra, T Becker, S Ohlraun… - Biological …, 2005 - Elsevier
BACKGROUND: Previous genetic studies investigating a possible involvement of variations
at the brain derived neurotrophic factor (BDNF) gene locus in major depressive disorder (…

[PDF][PDF] Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia

J Schumacher, H Anthoni, F Dahdouh, IR König… - The American Journal of …, 2006 - cell.com
We searched for linkage disequilibrium (LD) in 137 triads with dyslexia, using markers that
span the most-replicated dyslexia susceptibility region on 6p21-p22, and found association …

[PDF][PDF] Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder

…, TG Schulze, TF Wienker, J Schumacher… - The American Journal of …, 2011 - cell.com
We conducted a genome-wide association study (GWAS) and a follow-up study of bipolar
disorder (BD), a common neuropsychiatric disorder. In the GWAS, we investigated 499,494 …

[PDF][PDF] Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia

…, TG Schulze, HC Hennies, J Schumacher… - The American Journal of …, 2005 - cell.com
Androgenetic alopecia (AGA), or male-pattern baldness, is the most common form of hair
loss. Its pathogenesis is androgen dependent, and genetic predisposition is the major …

Genetics of dyslexia: the evolving landscape

J Schumacher, P Hoffmann, C Schmäl… - Journal of medical …, 2007 - jmg.bmj.com
Dyslexia is among the most common neurodevelopmental disorders, with a prevalence of 5–12%.
At the phenotypic level, various cognitive components that enable reading and …