User profiles for John F Mulley
John MulleySenior Lecturer, School of Natural Sciences, Bangor University Verified email at bangor.ac.uk Cited by 1327 |
[HTML][HTML] The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …
Restriction and recruitment—gene duplication and the origin and evolution of snake venom toxins
Snake venom has been hypothesized to have originated and diversified through a process
that involves duplication of genes encoding body proteins with subsequent recruitment of the …
that involves duplication of genes encoding body proteins with subsequent recruitment of the …
When one phenotype is not enough: Divergent evolutionary trajectories govern venom variation in a widespread rattlesnake species
…, DI Lannutti, JF Mulley… - … of the Royal …, 2019 - royalsocietypublishing.org
Understanding the origin and maintenance of phenotypic variation, particularly across a
continuous spatial distribution, represents a key challenge in evolutionary biology. For this, …
continuous spatial distribution, represents a key challenge in evolutionary biology. For this, …
Testing the Toxicofera: comparative transcriptomics casts doubt on the single, early evolution of the reptile venom system
The identification of apparently conserved gene complements in the venom and salivary
glands of a diverse set of reptiles led to the development of the Toxicofera hypothesis – the …
glands of a diverse set of reptiles led to the development of the Toxicofera hypothesis – the …
Inbred or outbred? Genetic diversity in laboratory rodent colonies
Nonmodel rodents are widely used as subjects for both basic and applied biological
research, but the genetic diversity of the study individuals is rarely quantified. University-housed …
research, but the genetic diversity of the study individuals is rarely quantified. University-housed …
Breakup of a homeobox cluster after genome duplication in teleosts
JF Mulley, C Chiu… - Proceedings of the …, 2006 - National Acad Sciences
Several families of homeobox genes are arranged in genomic clusters in metazoan
genomes, including the Hox, ParaHox, NK, Rhox, and Iroquois gene clusters. The selective …
genomes, including the Hox, ParaHox, NK, Rhox, and Iroquois gene clusters. The selective …
A new chromosome-assigned Mongolian gerbil genome allows characterization of complete centromeres and a fully heterochromatic chromosome
Chromosome-scale genome assemblies based on ultralong-read sequencing technologies
are able to illuminate previously intractable aspects of genome biology such as fine-scale …
are able to illuminate previously intractable aspects of genome biology such as fine-scale …
[HTML][HTML] Assessing the utility of the Oxford Nanopore MinION for snake venom gland cDNA sequencing
AD Hargreaves, JF Mulley - PeerJ, 2015 - peerj.com
Portable DNA sequencers such as the Oxford Nanopore MinION device have the potential
to be truly disruptive technologies, facilitating new approaches and analyses and, in some …
to be truly disruptive technologies, facilitating new approaches and analyses and, in some …
Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster
The sand rat Psammomys obesus is a gerbil species native to deserts of North Africa and
the Middle East, and is constrained in its ecology because high carbohydrate diets induce …
the Middle East, and is constrained in its ecology because high carbohydrate diets induce …
[HTML][HTML] Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate …
Background Understanding the evolution of the vertebrate pancreas is key to understanding
its functions. The chondrichthyes (cartilaginous fish such as sharks and rays) have often …
its functions. The chondrichthyes (cartilaginous fish such as sharks and rays) have often …