User profiles for John F Mulley

John Mulley

Senior Lecturer, School of Natural Sciences, Bangor University
Verified email at bangor.ac.uk
Cited by 1327

[HTML][HTML] The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

…, MS Campbell, D Barrell, KJ Martin, JF Mulley… - Nature …, 2016 - nature.com
To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …

Restriction and recruitment—gene duplication and the origin and evolution of snake venom toxins

…, MJ Hegarty, DW Logan, JF Mulley - Genome biology and …, 2014 - academic.oup.com
Snake venom has been hypothesized to have originated and diversified through a process
that involves duplication of genes encoding body proteins with subsequent recruitment of the …

When one phenotype is not enough: Divergent evolutionary trajectories govern venom variation in a widespread rattlesnake species

…, DI Lannutti, JF Mulley… - … of the Royal …, 2019 - royalsocietypublishing.org
Understanding the origin and maintenance of phenotypic variation, particularly across a
continuous spatial distribution, represents a key challenge in evolutionary biology. For this, …

Testing the Toxicofera: comparative transcriptomics casts doubt on the single, early evolution of the reptile venom system

AD Hargreaves, MT Swain, DW Logan, JF Mulley - Toxicon, 2014 - Elsevier
The identification of apparently conserved gene complements in the venom and salivary
glands of a diverse set of reptiles led to the development of the Toxicofera hypothesis – the …

Inbred or outbred? Genetic diversity in laboratory rodent colonies

TD Brekke, KA Steele, JF Mulley - G3: Genes, Genomes …, 2018 - academic.oup.com
Nonmodel rodents are widely used as subjects for both basic and applied biological
research, but the genetic diversity of the study individuals is rarely quantified. University-housed …

Breakup of a homeobox cluster after genome duplication in teleosts

JF Mulley, C Chiu… - Proceedings of the …, 2006 - National Acad Sciences
Several families of homeobox genes are arranged in genomic clusters in metazoan
genomes, including the Hox, ParaHox, NK, Rhox, and Iroquois gene clusters. The selective …

A new chromosome-assigned Mongolian gerbil genome allows characterization of complete centromeres and a fully heterochromatic chromosome

…, J Page, T Baril, A Hayward, JF Mulley - Molecular Biology …, 2023 - academic.oup.com
Chromosome-scale genome assemblies based on ultralong-read sequencing technologies
are able to illuminate previously intractable aspects of genome biology such as fine-scale …

[HTML][HTML] Assessing the utility of the Oxford Nanopore MinION for snake venom gland cDNA sequencing

AD Hargreaves, JF Mulley - PeerJ, 2015 - peerj.com
Portable DNA sequencers such as the Oxford Nanopore MinION device have the potential
to be truly disruptive technologies, facilitating new approaches and analyses and, in some …

Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster

…, BA Fox, WR Taylor, JF Mulley… - Proceedings of the …, 2017 - National Acad Sciences
The sand rat Psammomys obesus is a gerbil species native to deserts of North Africa and
the Middle East, and is constrained in its ecology because high carbohydrate diets induce …

[HTML][HTML] Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate …

JF Mulley, AD Hargreaves, MJ Hegarty, RS Heller… - BMC genomics, 2014 - Springer
Background Understanding the evolution of the vertebrate pancreas is key to understanding
its functions. The chondrichthyes (cartilaginous fish such as sharks and rays) have often …