Background About half of Americans 50 to 75 years old do not follow recommended colorectal
cancer (CRC) screening guidelines, leaving 40 million individuals unscreened. A simple …

Background & Aims Eosinophilic esophagitis is usually triggered by foods, by unclear
mechanisms. We evaluated the roles of IgE and IgG4 in the development of eosinophilic …

Tube feeding has been practiced for more than 400 years (1). In addition to feeding,
gastrointestinal (GI) access can be used for decompression in cases of enteral obstruction. …

OBJECTIVES: Elemental diets have not been studied in adults with eosinophilic esophagitis
(EoE). The goal of this trial was to assess the efficacy of an elemental diet in adults with EoE…

Background In a recent acute study, amantadine was found to have antidyskinetic effect against
levodopa-induced motor complications in patients with Parkinson disease. The longevity …

Background Both gastroesophageal reflux disease and allergy/atopy have been implicated
in the pathogenesis of eosinophilic esophagitis (EoE). There are no prospective studies …

Importance Urate elevation, despite associations with crystallopathic, cardiovascular, and
metabolic disorders, has been pursued as a potential disease-modifying strategy for …

Hybridization is a key molecular process in biology and biotechnology, but so far there is no
predictive model for accurately determining hybridization rate constants based on sequence …

OBJECTIVES: This article provides an overview of FDA's regulatory processes for drug
development and approval, and the estimated costs associated with the development of a drug, …

Background Teduglutide, an analog of glucagon-like peptide-2 (GLP-2), is associated with
trophic effects on gut mucosa. Its role in the treatment of active Crohn's disease (CD) was …