User profiles for John H. Connor
John ConnorBoston University/NEIDL Verified email at bu.edu Cited by 8574 |
Seeing protein monolayers with naked eye through plasmonic Fano resonances
We introduce an ultrasensitive label-free detection technique based on asymmetric Fano
resonances in plasmonic nanoholes with far reaching implications for point-of-care diagnostics. …
resonances in plasmonic nanoholes with far reaching implications for point-of-care diagnostics. …
An optofluidic nanoplasmonic biosensor for direct detection of live viruses from biological media
Fast and sensitive virus detection techniques, which can be rapidly deployed at multiple sites,
are essential to prevent and control future epidemics and bioterrorism threats. In this Letter…
are essential to prevent and control future epidemics and bioterrorism threats. In this Letter…
Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP
RD Blitzer, JH Connor, GP Brown, T Wong… - Science, 1998 - science.org
Long-term potentiation (LTP) at the Schaffer collateral–CA1 synapse involves interacting
signaling components, including calcium (Ca 2+ )/calmodulin–dependent protein kinase II (…
signaling components, including calcium (Ca 2+ )/calmodulin–dependent protein kinase II (…
Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1
The growth arrest and DNA damage-inducible protein, GADD34, was identified by its interaction
with human inhibitor 1 (I-1), a protein kinase A (PKA)-activated inhibitor of type 1 protein …
with human inhibitor 1 (I-1), a protein kinase A (PKA)-activated inhibitor of type 1 protein …
[HTML][HTML] Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA. 1 attenuation
The SARS-CoV-2 Omicron variant is more immune evasive and less virulent than other
major viral variants that have so far been recognized 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 – 12 . …
major viral variants that have so far been recognized 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 – 12 . …
Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway
Exosomes are secreted cellular vesicles that can be internalized by dendritic cells (DCs),
contributing to antigen-specific naive CD4 + T-cell activation. Here, we demonstrate that …
contributing to antigen-specific naive CD4 + T-cell activation. Here, we demonstrate that …
[PDF][PDF] Regulation of synaptic strength by protein phosphatase 1
We investigated the role of postsynaptic protein phosphatase 1 (PP1) in regulating synaptic
strength by loading CA1 pyramidal cells either with peptides that disrupt PP1 binding to …
strength by loading CA1 pyramidal cells either with peptides that disrupt PP1 binding to …
Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1
JH Connor, DS Lyles - Journal of virology, 2002 - Am Soc Microbiol
Vesicular stomatitis virus (VSV) modulates protein synthesis in infected cells in a way that
allows the translation of its own 5′-capped mRNA but inhibits the translation of host mRNA. …
allows the translation of its own 5′-capped mRNA but inhibits the translation of host mRNA. …
SARS-CoV-2 disrupts proximal elements in the JAK-STAT pathway
SARS-CoV-2 can infect multiple organs, including lung, intestine, kidney, heart, liver, and
brain. The molecular details of how the virus navigates through diverse cellular environments …
brain. The molecular details of how the virus navigates through diverse cellular environments …
[HTML][HTML] Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus
…, S Günther, AR Cossins, A Sprecher, JH Connor… - Genome biology, 2017 - Springer
Background In 2014, Western Africa experienced an unanticipated explosion of Ebola virus
infections. What distinguishes fatal from non-fatal outcomes remains largely unknown, yet is …
infections. What distinguishes fatal from non-fatal outcomes remains largely unknown, yet is …