User profiles for John H. McCusker

John McCusker

Duke University Medical Center
Verified email at duke.edu
Cited by 9796

Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae

AL Goldstein, JH McCusker - Yeast, 1999 - Wiley Online Library
… separately, into one copy of the ho locus of YJM237 (McCusker … cassettes were
integrated into one copy of the ho locus of the prototrophic S288c diploid strain YJM237 (McCusker

Yeast microarrays for genome wide parallel genetic and gene expression analysis

DA Lashkari, JL DeRisi, JH McCusker… - Proceedings of the …, 1997 - National Acad Sciences
We have developed high-density DNA microarrays of yeast ORFs. These microarrays can
monitor hybridization to ORFs for applications such as quantitative differential gene …

Dissecting the architecture of a quantitative trait locus in yeast

…, DR Richards, JI Spiegelman, PJ Oefner, JH McCusker… - Nature, 2002 - nature.com
Most phenotypic diversity in natural populations is characterized by differences in degree
rather than in kind. Identification of the actual genes underlying these quantitative traits has …

[HTML][HTML] Calcineurin is essential for survival during membrane stress in Candida albicans

…, ME Cardenas, JR Perfect, JH McCusker… - The EMBO …, 2002 - embopress.org
The immunosuppressants cyclosporin A (CsA) and FK506 inhibit the protein phosphatase
calcineurin and block T‐cell activation and transplant rejection. Calcineurin is conserved in …

The 100-genomes strains, an S. cerevisiae resource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen

…, PM Magwene, FS Dietrich, JH McCusker - Genome …, 2015 - genome.cshlp.org
Saccharomyces cerevisiae, a well-established model for species as diverse as humans and
pathogenic fungi, is more recently a model for population and quantitative genetics. S. …

Direct allelic variation scanning of the yeast genome

…, S Kalman, MJ McCullough, JH McCusker… - Science, 1998 - science.org
As more genomes are sequenced, the identification and characterization of the causes of
heritable variation within a species will be increasingly important. It is demonstrated that allelic …

Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789

W Wei, JH McCusker, RW Hyman… - Proceedings of the …, 2007 - National Acad Sciences
We sequenced the genome of Saccharomyces cerevisiae strain YJM789, which was derived
from a yeast isolated from the lung of an AIDS patient with pneumonia. The strain is used …

Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production

…, AR Alcarde, FS Dietrich, JH McCusker… - Genome …, 2009 - genome.cshlp.org
Bioethanol is a biofuel produced mainly from the fermentation of carbohydrates derived
from agricultural feedstocks by the yeast Saccharomyces cerevisiae. One of the most widely …

Genetic characterization of pathogenic Saccharomyces cerevisiae isolates.

JH McCusker, KV Clemons, DA Stevens, RW Davis - Genetics, 1994 - academic.oup.com
Saccharomyces cerevisiae isolates from human patients have been genetically analyzed.
Some of the characteristics of these isolates are very different from laboratory and industrial …

Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast

…, G Shi, J Dean, RW Davis, PJ Oefner, JH McCusker… - Genetics, 2008 - academic.oup.com
Several quantitative trait loci (QTL) mapping strategies can successfully identify major-effect
loci, but often have poor success detecting loci with minor effects, potentially due to the …