HOX genes specify cell fate in the anterior-posterior axis of animal embryos. Invertebrate
chordates have one HOXcluster, but mammals have four, suggesting that cluster duplication …

The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of
lobe-finned fish was thought to have become extinct 70 million years ago. The modern …

To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …

To facilitate molecular genetic analysis of vertebrate development, haploid genetics was
used to construct a recombination map for the zebrafish Danio (Brachydanio) rerio. The map …

Within vertebrates, major sex determining genes can differ among taxa and even within
species. In zebrafish (Danio rerio), neither heteromorphic sex chromosomes nor single sex …

In chordate phylogeny, changes in the nervous system, jaws, and appendages transformed
meek filter feeders into fearsome predators1. Gene duplication is thought to promote such …

To help understand mechanisms of vertebrate genome evolution, we have compared
zebrafish and tetrapod gene maps. It has been suggested that translocations are fixed more …

Zebrafish mutations define the functions of hundreds of essential genes in the vertebrate
genome. To accelerate the molecular analysis of zebrafish mutations and to facilitate …

The notochord is a midline mesodermal structure with an essential patterning function in all
vertebrate embryos. Zebrafish floating head (flh) mutants lack a notochord, but develop with …

Advances in sequencing technology provide special opportunities for genotyping individuals
with speed and thrift, but the lack of software to automate the calling of tens of thousands of …