“Functional” tumor treatment response parameters have been developed to measure
treatment induced biochemical changes in the entire tumor mass, using positron emission …

BACKGROUND It is common protocol in radionuclide therapies to administer a tracer dose
of a radiopharmaceutical, determine its lesion uptake and biodistribution by gamma imaging, …

Unlike β particle–emitting isotopes, α emitters can selectively kill individual cancer cells with
a single atomic decay. HuM195, a humanized anti-CD33 monoclonal antibody, specifically …

This review discusses the application of alpha particle-emitting radionuclides in targeted
radioimmunotherapy. It will outline the production and chemistry of astatine-211, bismuth-212, …

We have developed a new technique to gate lung 18 F-FDG PET images in synchronization
with the respiratory motion to reduce smearing due to breathing and improve quantitation of …

Purpose: Many patients with non-small cell lung cancer (NSCLC) receive external beam
radiation therapy as part of their treatment. Three-dimensional conformal radiation therapy (…

This trial was an initial assessment of the feasibility, in vivo targeting, and biokinetics of 16β-
18 F-fluoro-5α-dihydrotestosterone ( 18 F-FDHT) PET in patients with metastatic prostate …

We previously reported that respiratory motion is a major source of error in quantitation of
lesion activity using combined PET/CT units. CT acquisition of the lesion occurs in seconds, …

This review describes the properties of available and emerging radiation detector and read-out
technologies and discusses how they may affect PET scanner performance. After a …

PURPOSE: We investigate the characteristics of lung tumor motion measured with
respiration-correlated computed tomography (RCCT) and examine the method's applicability to …