By homologous recombination of an internal ribosome entry site and Cre recombinase coding
region into the 3′-untranslated region of the mouse Emx1 gene, we have generated a …

… ; the other mouse probes were isolated in the Rubenstein lab and details can be found in the
… Other chick probes were isolated in the Rubenstein lab and details (also listed in Table 1) …

Directed differentiation from human pluripotent stem cells (hPSCs) has seen significant progress
in recent years. However, most differentiated populations exhibit immature properties of …

The success of vertebrates was due in part to the acquisition and modification of jaws. Jaws
are principally derived from the branchial arches, embryonic structures that exhibit …

The mammalian telencephalon is considered the most complex of all biological structures. It
comprises a large number of functionally and morphologically distinct types of neurons that …

Mutations in the X-linked MECP2 gene, which encodes the transcriptional regulator methyl-CpG-binding
protein 2 (MeCP2), cause Rett syndrome and several neurodevelopmental …

Recent studies on the origin of cell populations in rodent and chicken embryonic brains provide
evidence for extensive tangential migration within the developing telencephalon. On the …

▪ Abstract The forebrain comprises an intricate set of structures that are required for some of
the most complex and evolved functions of the mammalian brain. As a reflection of its …

The molecular mechanisms that control regional specification, morphogenesis and differentiation
of the embryonic forebrain are not known, although recently seueral laboratories haue …

The cerebral cortex of the human brain is a sheet of about 10 billion neurons divided into
discrete subdivisions or areas that process particular aspects of sensation, movement, and …