User profiles for John M. Errico

John M. Errico

Scientist, Vir Biotechnology
Verified email at vir.bio
Cited by 3135

[HTML][HTML] An infectious SARS-CoV-2 B. 1.1. 529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies

LA VanBlargan, JM Errico, PJ Halfmann, SJ Zost… - Nature medicine, 2022 - nature.com
The emergence of the highly transmissible B.1.1.529 Omicron variant of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody countermeasure …

[HTML][HTML] Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

…, ES Winkler, Y Liu, LA VanBlargan, J Liu, JM Errico… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global
COVID-19 pandemic. Rapidly spreading SARS-CoV-2 variants may jeopardize newly …

[PDF][PDF] Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

…, PW Rothlauf, RE Chen, S Stumpf, H Zhao, JM Errico… - Cell host & …, 2021 - cell.com
Neutralizing antibodies against the SARS-CoV-2 spike (S) protein are a goal of COVID-19
vaccines and have received emergency use authorization as therapeutics. However, viral …

[HTML][HTML] In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

…, TL Bricker, A Joshi, TL Darling, B Ying, JM Errico… - Nature, 2021 - nature.com
Rapidly emerging SARS-CoV-2 variants jeopardize antibody-based countermeasures.
Although cell culture experiments have demonstrated a loss of potency of several anti-spike …

Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

…, PW Rothlauf, RE Chen, S Stumpf, H Zhao, JM Errico… - BioRxiv, 2020 - biorxiv.org
Although neutralizing antibodies against the SARS-CoV-2 spike (S) protein are a goal of
most COVID-19 vaccines and being developed as therapeutics, escape mutations could …

[PDF][PDF] Affinity-restricted memory B cells dominate recall responses to heterologous flaviviruses

…, J Govero, JL Uhrlaub, D Reinartz, H Zhao, JM Errico… - Immunity, 2020 - cell.com
Memory B cells (MBCs) can respond to heterologous antigens either by molding new
specificities through secondary germinal centers (GCs) or by selecting preexisting clones without …

[HTML][HTML] Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains

JB Case, S Mackin, JM Errico, Z Chong… - Nature …, 2022 - nature.com
Omicron variant strains encode large numbers of changes in the spike protein compared to
historical SARS-CoV-2 isolates. Although in vitro studies have suggested that several …

[HTML][HTML] On the road to ending the COVID-19 pandemic: Are we there yet?

JB Case, ES Winkler, JM Errico, MS Diamond - Virology, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged into the human
population in late 2019 and caused the global COVID-19 pandemic. SARS-CoV-2 has spread …

A cohort of new adhesive proteins identified from transcriptomic analysis of mussel foot glands

DG DeMartini, JM Errico… - Journal of the …, 2017 - royalsocietypublishing.org
The adaptive attachment of marine mussels to a wide range of substrates in a high-energy,
saline environment has been explored for decades and is a significant driver of bioinspired …

Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8

…, MI Zimmerman, S Raju, CA Nelson, JM Errico… - Cell, 2023 - cell.com
MXRA8 is a receptor for chikungunya (CHIKV) and other arthritogenic alphaviruses with
mammalian hosts. However, mammalian MXRA8 does not bind to alphaviruses that infect …