In the 18th century, Thomas Bayes developed his eponymous theorem that teaches us that
pretest probabilities can be altered by new information, such as when game show host Monty …

The phagocyte respiratory burst is crucial for innate immunity. The transfer of electrons to
oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22phox …

Tumor necrosis factor receptor–associated factor 3 (TRAF3) is a central regulator of immunity.
TRAF3 is often somatically mutated in B cell malignancies, but its role in human immunity …

Objective: To describe the effect of antibiotics on outcomes of treatment for Buruli or Bairnsdale
ulcer (BU) in patients on the Bellarine Peninsula in south‐eastern Australia. Design: …

Background Inborn errors of immunity (IEI) present with a large phenotypic spectrum of
disease, which can pose diagnostic and therapeutic challenges. Suppressor of cytokine …

Several tolerance checkpoints exist throughout B cell development to control autoreactive B
cells and prevent the generation of pathogenic autoantibodies. FcγRIIb is an Fc receptor that …

Mutations in the human NBEAL2 gene cause gray platelet syndrome (GPS), a bleeding
diathesis characterized by a lack of α granules in platelets. The functions of the NBEAL2 protein …

EROS (essential for reactive oxygen species) protein is indispensable for expression of
gp91phox, the catalytic core of the phagocyte NADPH oxidase. EROS deficiency in humans is a …

The generation of a potent humoral immune response by B cells relies on the integration of
signals induced by the B cell receptor, toll-like receptors and both negative and positive co-…

EROS (Essential for Reactive Oxygen Species) protein is indispensable for expression of
the gp91phox-p22phox heterodimer of the phagocyte NADPH oxidase. EROS deficiency in …