RESULTS AND DISCUSSION 1. In our hands, this procedure yields more DNA than any
other methods (1-5), generally in the range of 130-160. tg from 5 ml of blood. We have also …

This the Diagnostic Interview for Genetic Studies (DIGS), a clinical interview especially
constructed for the assessment of major mood and psychotic disorders and their spectrum …

Autism spectrum disorders (ASDs) are childhood neurodevelopmental disorders with complex
genetic origins 1 , 2 , 3 , 4 . Previous studies focusing on candidate genes or genomic …

Autism spectrum disorders (ASDs) represent a group of childhood neurodevelopmental and
neuropsychiatric disorders characterized by deficits in verbal communication, impairment of …

• In a family study of 1,254 adult relatives of patients and controls, lifetime prevalences of
major affective disorder (including schizoaffective) were 37%, 24%, 25%, 20% and 7% in …

Rare copy-number variation (CNV) is an important source of risk for autism spectrum
disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic …

Alcohol dependence is a leading cause of morbidity and premature death. Several lines of
evidence suggest a substantial genetic component to the risk for alcoholism: sibs of alcoholic …

Alcoholism is a complex disease with both genetic and environmental risk factors. To
identify genes that affect the risk for alcoholism, we systematically ascertained and carefully …

Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic
architecture or its genetic relationship with other disorders. To discover loci associated …

Using data from The Collaborative Study on the Genetics of Alcoholism, we compare direct
interview diagnoses of alcohol dependence to those obtained by history from family members…