User profiles for John P. Horn
John P. HornProfessor of Neurobiology Verified email at pitt.edu Cited by 2117 |
Cav1. 3 channel voltage dependence, not Ca2+ selectivity, drives pacemaker activity and amplifies bursts in nigral dopamine neurons
I Putzier, PHM Kullmann, JP Horn… - Journal of …, 2009 - Soc Neuroscience
Ca v 1.3 (α1D) L-type Ca 2+ channels have been implicated in substantia nigra (SN) dopamine
(DA) neuron pacemaking and vulnerability to Parkinson's disease. These effects may …
(DA) neuron pacemaking and vulnerability to Parkinson's disease. These effects may …
Pacemaker rate and depolarization block in nigral dopamine neurons: a somatic sodium channel balancing act
KR Tucker, MA Huertas, JP Horn… - Journal of …, 2012 - Soc Neuroscience
Midbrain dopamine (DA) neurons are slow intrinsic pacemakers that undergo depolarization
(DP) block upon moderate stimulation. Understanding DP block is important because it has …
(DP) block upon moderate stimulation. Understanding DP block is important because it has …
Implementation of a fast 16-bit dynamic clamp using LabVIEW-RT
…, DW Wheeler, J Beacom, JP Horn - Journal of …, 2004 - journals.physiology.org
The dynamic-clamp method provides a powerful electrophysiological tool for creating virtual
ionic conductances in living cells and studying their influence on membrane potential. Here …
ionic conductances in living cells and studying their influence on membrane potential. Here …
Physiological classification of sympathetic neurons in the rat superior cervical ganglion
C Li, JP Horn - Journal of neurophysiology, 2006 - journals.physiology.org
A new scheme is presented for identifying three sympathetic phenotypes in the rat superior
cervical ganglion using electrophysiology and neuropeptide Y expression. Postganglionic …
cervical ganglion using electrophysiology and neuropeptide Y expression. Postganglionic …
Functional characterization of ether‐à‐go‐go‐related gene potassium channels in midbrain dopamine neurons–implications for a role in depolarization block
…, I Putzier, MA Huertas, JP Horn… - European Journal of …, 2012 - Wiley Online Library
Bursting activity by midbrain dopamine neurons reflects the complex interplay between their
intrinsic pacemaker activity and synaptic inputs. Although the precise mechanism …
intrinsic pacemaker activity and synaptic inputs. Although the precise mechanism …
Virtual leak channels modulate firing dynamics and synaptic integration in rat sympathetic neurons: implications for ganglionic transmission in vivo
…, PHM Kullmann, JP Horn - The Journal of …, 2015 - Wiley Online Library
Key points The synaptic organization of paravertebral sympathetic ganglia enables them to
relay activity from the spinal cord to the periphery and thereby control autonomic functions, …
relay activity from the spinal cord to the periphery and thereby control autonomic functions, …
[HTML][HTML] The sacral autonomic outflow is parasympathetic: Langley got it right
JP Horn - Clinical Autonomic Research, 2018 - Springer
A recent developmental study of gene expression by Espinosa-Medina, Brunet and colleagues
sparked controversy by asserting a revised nomenclature for divisions of the autonomic …
sparked controversy by asserting a revised nomenclature for divisions of the autonomic …
A reclassification of B and C neurones in the ninth and tenth paravertebral sympathetic ganglia of the bullfrog.
J Dodd, JP Horn - The Journal of physiology, 1983 - Wiley Online Library
1. The cellular organization of the ninth and tenth paravertebral sympathetic ganglia in the
bullfrog was studied with intracellular and extracellular recording methods. An isolated …
bullfrog was studied with intracellular and extracellular recording methods. An isolated …
Continuous repetitive stimuli are more effective than bursts for evoking LHRH release in bullfrog sympathetic ganglia
YY Peng, JP Horn - Journal of Neuroscience, 1991 - Soc Neuroscience
Effects of different patterns of presynaptic stimulation upon release of leuteinizing hormone
releasing hormone (LHRH) were studied by monitoring LHRH-induced slow currents from …
releasing hormone (LHRH) were studied by monitoring LHRH-induced slow currents from …
D2 autoreceptors chronically enhance dopamine neuron pacemaker activity
J Hahn, PHM Kullmann, JP Horn… - Journal of …, 2006 - Soc Neuroscience
Activation of D 2 autoreceptors on midbrain dopamine neurons has been shown previously
to acutely open K + channels to inhibit intrinsically generated pacemaker activity. Here we …
to acutely open K + channels to inhibit intrinsically generated pacemaker activity. Here we …