Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study
…, E Wajswol, JS Winoker, JP Sfakianos… - Proceedings of the …, 2019 - National Acad Sciences
Biocompatible gold nanoparticles designed to absorb light at wavelengths of high tissue
transparency have been of particular interest for biomedical applications. The ability of such …
transparency have been of particular interest for biomedical applications. The ability of such …
The effect of age and gender on bladder cancer: a critical review of the literature
SF Shariat, JP Sfakianos, MJ Droller… - BJU …, 2010 - Wiley Online Library
While patient age and gender are important factors in the clinical decision‐making for
treating urothelial carcinoma of the bladder (UCB), there are no evidence‐based …
treating urothelial carcinoma of the bladder (UCB), there are no evidence‐based …
[HTML][HTML] EMT-and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
…, A Siefker-Radtke, P Sharma, JP Sfakianos… - Nature …, 2018 - nature.com
Cancers infiltrated with T-cells are associated with a higher likelihood of response to PD-1/PD-L1
blockade. Counterintuitively, a correlation between epithelial–mesenchymal transition (…
blockade. Counterintuitively, a correlation between epithelial–mesenchymal transition (…
Genomic characterization of upper tract urothelial carcinoma
… Author links open overlay panel John P. Sfakianos a b , Eugene K. Cha a , Gopa Iyer c d , …
Sfakianos was a research fellow in urologic oncology supported by NIH T32-CA82088. …
Sfakianos was a research fellow in urologic oncology supported by NIH T32-CA82088. …
[PDF][PDF] NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer
Programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1)-blockade
immunotherapies have limited efficacy in the treatment of bladder cancer. Here, we show that …
immunotherapies have limited efficacy in the treatment of bladder cancer. Here, we show that …
Effectiveness of adjuvant chemotherapy for locally advanced bladder cancer
…, KD Stensland, E Moshier, JP Sfakianos… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Given that randomized trials exploring adjuvant chemotherapy for bladder cancer
have been underpowered and/or terminated prematurely, yielding inconsistent results and …
have been underpowered and/or terminated prematurely, yielding inconsistent results and …
The effect of restaging transurethral resection on recurrence and progression rates in patients with nonmuscle invasive bladder cancer treated with intravesical …
JP Sfakianos, PH Kim, AA Hakimi, HW Herr - The Journal of urology, 2014 - Elsevier
Purpose We determined whether restaging resection before initiating induction intravesical
bacillus Calmette-Guérin improves the recurrence-free rate in patients with high risk …
bacillus Calmette-Guérin improves the recurrence-free rate in patients with high risk …
Clonal relatedness and mutational differences between upper tract and bladder urothelial carcinoma
…, EJ Pietzak, JP Sfakianos, A Bagrodia, P Murugan… - Clinical Cancer …, 2019 - AACR
Purpose: To investigate genomic differences between urothelial carcinomas of the upper
tract (UTUC) and bladder (UCB), with a focus on defining the clonal relatedness of temporally …
tract (UTUC) and bladder (UCB), with a focus on defining the clonal relatedness of temporally …
Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladder
Urothelial carcinoma of the bladder (UCB) is genomically heterogeneous, with frequent
alterations in genes regulating chromatin state, cell cycle control, and receptor kinase signaling. …
alterations in genes regulating chromatin state, cell cycle control, and receptor kinase signaling. …
[HTML][HTML] Genetic determinants of cisplatin resistance in patients with advanced germ cell tumors
Purpose Owing to its exquisite chemotherapy sensitivity, most patients with metastatic germ
cell tumors (GCTs) are cured with cisplatin-based chemotherapy. However, up to 30% of …
cell tumors (GCTs) are cured with cisplatin-based chemotherapy. However, up to 30% of …