User profiles for John P. Wikswo

John Wikswo

University Distinguished Professor; AB Learned Professor, Founding Director of VIIBRE
Verified email at vanderbilt.edu
Cited by 18402

Using a magnetometer to image a two‐dimensional current distribution

BJ Roth, NG Sepulveda, JP Wikswo Jr - Journal of applied physics, 1989 - pubs.aip.org
We describe a mathematical algorithm to obtain an image of a two‐dimensional current
distribution from measurements of its magnetic field. The spatial resolution of this image is …

[HTML][HTML] Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

…, D Li, AB Bowman, RS Reiserer, JP Wikswo - …, 2015 - pubs.aip.org
The blood-brain barrier (BBB) is a critical structure that serves as the gatekeeper between
the central nervous system and the rest of the body. It is the responsibility of the BBB to …

[HTML][HTML] Scaling and systems biology for integrating multiple organs-on-a-chip

JP Wikswo, EL Curtis, ZE Eagleton, BC Evans, A Kole… - Lab on a Chip, 2013 - pubs.rsc.org
Coupled systems of in vitro microfabricated organs-on-a-chip containing small populations
of human cells are being developed to address the formidable pharmacological and …

Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator

…, A Richmond, M Stremler, CY Chung, JP Wikswo - Lab on a Chip, 2005 - pubs.rsc.org
An understanding of chemotaxis at the level of cell–molecule interactions is important because
of its relevance in cancer, immunology, and microbiology, just to name a few. This study …

Magnetic field of a nerve impulse: first measurements

JP Wikswo, JP Barach, JA Freeman - Science, 1980 - science.org
… In view of this possibility, we may assign it the weight 1/3" (p. 392). The need for such
extraordinary observation-by-observation analysis was dictated by the presence of systematic …

Microfluidic single-cell array cytometry for the analysis of tumor apoptosis

D Wlodkowic, S Faley, M Zagnoni, JP Wikswo… - Analytical …, 2009 - ACS Publications
Limitations imposed by conventional analytical technologies for cell biology, such as flow
cytometry or microplate imaging, are often prohibitive for the kinetic analysis of single-cell …

A low temperature transfer of ALH84001 from Mars to Earth

…, H Vali, NT Peters, FA Macdonald, JP Wikswo - Science, 2000 - science.org
The ejection of material from Mars is thought to be caused by large impacts that would heat
much of the ejecta to high temperatures. Images of the magnetic field of martian meteorite …

The relevance and potential roles of microphysiological systems in biology and medicine

JP Wikswo - Experimental biology and medicine, 2014 - journals.sagepub.com
… roles of microphysiological systems in biology and medicine - John P Wikswo, 2014 …
Subramaniam S, Van der Graaf P, Vicini P. Quantitative and systems pharmacology … John P

[HTML][HTML] Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle

…, M Estes, J Himmelfarb, G Truskey, JP Wikswo… - Scientific reports, 2017 - nature.com
Organ interactions resulting from drug, metabolite or xenobiotic transport between organs are
key components of human metabolism that impact therapeutic action and toxic side effects. …

Engineering challenges for instrumenting and controlling integrated organ-on-chip systems

JP Wikswo, FE Block III, DE Cliffel… - IEEE Transactions …, 2013 - ieeexplore.ieee.org
The sophistication and success of recently reported microfabricated organs-on-chips and
human organ constructs have made it possible to design scaled and interconnected organ …