[HTML][HTML] Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
…, H Thieme, MA Iwamoto, JE Park… - … England Journal of …, 1994 - Mass Medical Soc
Background Retinal ischemia induces intraocular neovascularization, which often leads to
glaucoma, vitreous hemorrhage, and retinal detachment, presumably by stimulating the …
glaucoma, vitreous hemorrhage, and retinal detachment, presumably by stimulating the …
[HTML][HTML] Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
…, JA Butman, K Camphausen, J Park… - Journal of clinical …, 2009 - ncbi.nlm.nih.gov
Results Forty-eight heavily pretreated patients were accrued to this study. Thromboembolic
events (12.5%), hypertension (12.5%), hypophosphatemia (6%), and thrombocytopenia (6%) …
events (12.5%), hypertension (12.5%), hypophosphatemia (6%), and thrombocytopenia (6%) …
[PDF][PDF] Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum …
…, BW Purow, N Christopher, W Zhang, JK Park… - Cancer cell, 2006 - cell.com
The concept of tumor stem cells (TSCs) provides a new paradigm for understanding tumor
biology, although it remains unclear whether TSCs will prove to be a more robust model than …
biology, although it remains unclear whether TSCs will prove to be a more robust model than …
Challenges in representation learning: A report on three machine learning contests
The ICML 2013 Workshop on Challenges in Representation Learning focused on three
challenges: the black box learning challenge, the facial expression recognition challenge, and …
challenges: the black box learning challenge, the facial expression recognition challenge, and …
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.
The recently identified placenta growth factor (PIGF) is a member of the vascular endothelial
growth factor (VEGF) family of growth factors. PIGF displays a 53% identity with the platelet-…
growth factor (VEGF) family of growth factors. PIGF displays a 53% identity with the platelet-…
Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
…, K Hong, UB Nielsen, JD Marks, CC Benz, JW Park - Cancer research, 2006 - AACR
We describe evidence for a novel mechanism of monoclonal antibody (MAb)–directed
nanoparticle (immunoliposome) targeting to solid tumors in vivo. Long-circulating …
nanoparticle (immunoliposome) targeting to solid tumors in vivo. Long-circulating …
The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound …
Vascular endothelial growth factor (VEGF)mRNA undergoes alternative splicing events that
generate four different homodimeric isoforms, VEGF121, VEGF165, VEGF189, or VEGF206. …
generate four different homodimeric isoforms, VEGF121, VEGF165, VEGF189, or VEGF206. …
Identification of Heregulin, a Specific Activator of p185erbB2
…, MX Sliwkowski, RW Akita, WJ Henzel, J Lee, JW Park… - Science, 1992 - science.org
The proto-oncogene designated erbB2 or HER2 encodes a 185-kilodalton transmembrane
tyrosine kinase (p185 erbB2 ), whose overexpression has been correlated with a poor …
tyrosine kinase (p185 erbB2 ), whose overexpression has been correlated with a poor …
[HTML][HTML] The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo
…, S Thomas, E Kinetz, DL Compton, E Rojas, JS Park… - Cell, 1996 - cell.com
Formation of neuromuscular synapses requires a series of inductive interactions between
growing motor axons and differentiating muscle cells, culminating in the precise juxtaposition …
growing motor axons and differentiating muscle cells, culminating in the precise juxtaposition …
Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery
JW Park, K Hong, DB Kirpotin, G Colbern… - Clinical Cancer …, 2002 - AACR
Purpose: Anti-HER2 immunoliposomes combine the tumor-targeting of certain anti-HER2
monoclonal antibodies (MAbs) with the pharmacokinetic and drug delivery capabilities of …
monoclonal antibodies (MAbs) with the pharmacokinetic and drug delivery capabilities of …