An abundance of X-linked genes expressed in spermatogonia

PJ Wang, JR McCarrey, F Yang, DC Page - Nature genetics, 2001 - nature.com
Spermatogonia are the self-renewing, mitotic germ cells of the testis from which sperm arise
by means of the differentiation pathway known as spermatogenesis 1. By contrast with …

Toward a more precise and informative nomenclature describing fetal and neonatal male germ cells in rodents

JR McCarrey - Biology of reproduction, 2013 - academic.oup.com
The germ cell lineages are among the best characterized of all cell lineages in mammals.
This characterization includes precise nomenclature that distinguishes among numerous, …

[HTML][HTML] Advantages of nonhuman primates as preclinical models for evaluating stem cell-based therapies for Parkinson's disease

DA Grow, JR McCarrey, CS Navara - Stem cell research, 2016 - Elsevier
The derivation of dopaminergic neurons from induced pluripotent stem cells brings new hope
for a patient-specific, stem cell-based replacement therapy to treat Parkinson's disease (PD…

The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis

JE Shima, DJ McLean, JR McCarrey… - Biology of …, 2004 - academic.oup.com
One of the most promising applications of microarrays is the study of changes in gene
expression associated with the growth and development of mammalian tissues. The testis …

Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene

JR McCarrey, K Thomas - Nature, 1987 - nature.com
Phosphoglycerate kinase (PGK) (ATP: 3-phospho-D-glycerate 1-phosphotransferase, EC
2.7.2.3) is a metabolic enzyme functioning in the Embden–Meyerhof pathway that converts …

The H19 methylation imprint is erased and re‐established differentially on the parental alleles during male germ cell development

TL Davis, GJ Yang, JR McCarrey… - Human molecular …, 2000 - academic.oup.com
Differences in DNA methylation distinguish the maternal and paternal alleles of many
imprinted genes. Allele-specific methylation that is inherited from the gametes and maintained …

[PDF][PDF] The mammalian spermatogenesis single-cell transcriptome, from spermatogonial stem cells to spermatids

…, D Fritze, S Silber, CB Geyer, JM Oatley, JR McCarrey - Cell reports, 2018 - cell.com
Spermatogenesis is a complex and dynamic cellular differentiation process critical to male
reproduction and sustained by spermatogonial stem cells (SSCs). Although patterns of gene …

[HTML][HTML] Postmeiotic sex chromatin in the male germline of mice

…, PJ Park, LF Zhang, JE Shima, JR McCarrey… - Current Biology, 2006 - cell.com
In mammals, the X and Y chromosomes are subject to meiotic sex chromosome inactivation
(MSCI) during prophase I in the male germline, but their status thereafter is currently unclear. …

Expression of Stimulated by Retinoic Acid Gene 8 (Stra8) and Maturation of Murine Gonocytes and Spermatogonia Induced by Retinoic Acid In Vitro

…, D Pouchnik, B Banasik, JR McCarrey… - Biology of …, 2008 - academic.oup.com
Vitamin A deficiency in the mouse results in an arrest in the progression of undifferentiated
spermatogonia to differentiating spermatogonia. The supplement of retinol to vitamin-A-…

[HTML][HTML] Cloning and expression profiling of testis-expressed microRNAs

S Ro, C Park, KM Sanders, JR McCarrey, W Yan - Developmental biology, 2007 - Elsevier
Using a new small RNA cloning method, we identified 141 miRNAs from the mouse testis, of
which 29 were novel. The 141 miRNAs were mapped onto all chromosomes except the Y …