Background Limited clinical and laboratory data are available on patients with Ebola virus
disease (EVD). The Kenema Government Hospital in Sierra Leone, which had an existing …

The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …

The 2013–2015 Ebola virus disease (EVD) epidemic is caused by the Makona variant of
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …

The 2013–2015 West African epidemic of Ebola virus disease (EVD) reminds us of how little
is known about biosafety level 4 viruses. Like Ebola virus, Lassa virus (LASV) can cause …

Background Lassa fever (LF), an often-fatal hemorrhagic disease caused by Lassa virus (LASV),
is a major public health threat in West Africa. When the violent civil conflict in Sierra …

… Because sepsis itself cannot be identified with certainty, predictive validity instead evaluates
a potential criterion’s ability to identify, from among patients at risk for sepsis, those more …

Lassa fever is a severe multisystem disease that often has haemorrhagic manifestations. The
epitopes of the Lassa virus (LASV) surface glycoproteins recognized by naturally infected …

The recent large outbreak of Ebola virus disease (EVD) in Western Africa resulted in greatly
increased accumulation of human genotypic, phenotypic and clinical data, and improved our …

As of 20 May 2016 there have been 28,646 cases and 11,323 deaths resulting from the
West African Ebola virus disease (EVD) outbreak reported to the World Health Organization. …

Background Zoonotic infections, which transmit from animals to humans, form the majority of
new human pathogens. Following zoonotic transmission, the pathogen may already have, …