User profiles for John Trefry

John Trefry

Professor of Oceanography, Florida Institute of Technology
Verified email at fit.edu
Cited by 5565

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

…, BS Graham, JJ Muyembe-Tamfun, JC Trefry… - Science, 2016 - science.org
Ebola virus disease in humans is highly lethal, with case fatality rates ranging from 25 to 90%.
There is no licensed treatment or vaccine against the virus, underscoring the need for …

[HTML][HTML] Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge

DA Stanley, AN Honko, C Asiedu, JC Trefry… - Nature medicine, 2014 - nature.com
Ebolavirus disease causes high mortality, and the current outbreak has spread unabated
through West Africa. Human adenovirus type 5 vectors (rAd5) encoding ebolavirus …

Chemical and mineralogical influences on concentrations of trace metals in hydrothermal fluids

S Metz, JH Trefry - Geochimica et Cosmochimica Acta, 2000 - Elsevier
Concentrations of trace metals in hydrothermal solutions from the southern Juan de Fuca
Ridge (SJFR) and the TAG Hydrothermal Field on the Mid-Atlantic Ridge are influenced by the …

Development of clinical-stage human monoclonal antibodies that treat advanced Ebola virus disease in nonhuman primates

KE Pascal, D Dudgeon, JC Trefry… - The Journal of …, 2018 - academic.oup.com
Background For most classes of drugs, rapid development of therapeutics to treat emerging
infections is challenged by the timelines needed to identify compounds with the desired …

Role of hydrothermal precipitates in the geochemical cycling of vanadium

JH Trefry, S Metz - Nature, 1989 - nature.com
THE input of high-temperature fluids to the ocean along sea-floor spreading centres plays
an important part in controlling the composition of sea water 1–3 . Available data 1–3 show …

Distribution and chemistry of suspended particles from an active hydrothermal vent site on the Mid-Atlantic Ridge at 26 N

RP Trocine, JH Trefry - Earth and Planetary Science Letters, 1988 - Elsevier
Suspended particles were collected from an area of active hydrothermal venting at the Trans-Atlantic
Geotraverse (TAG) Hydrothermal Field on the Mid-Atlantic Ridge and analyzed for …

Increased concentrations of dissolved trace metals and organic carbon during snowmelt in rivers of the Alaskan Arctic

RD Rember, JH Trefry - Geochimica et Cosmochimica Acta, 2004 - Elsevier
Arctic rivers typically transport more than half of their annual amounts of water and suspended
sediments during spring floods. In this study, the Sagavanirktok, Kuparuk and Colville …

Composition and sedimentation of hydrothermal plume particles from North Cleft segment, Juan de Fuca Ridge

RA Feely, GJ Massoth, JH Trefry… - Journal of …, 1994 - Wiley Online Library
In 1990 and 1991, particles from buoyant and neutrally buoyant hydrothermal plumes above
hydrothermal vents at the North Cleft segment of the Juan de Fuca Ridge were sampled to …

A decline in lead transport by the Mississippi River

JH Trefry, S Metz, RP Trocine, TA Nelsen - Science, 1985 - science.org
Inputs of pollutant lead to the Gulf of Mexico from the Mississippi River have declined by about
40 percent within the past decade. This decrease has been determined from annual lead …

[HTML][HTML] Potential vaccines and post-exposure treatments for filovirus infections

BM Friedrich, JC Trefry, JE Biggins, LE Hensley… - Viruses, 2012 - mdpi.com
Viruses of the family Filoviridae represent significant health risks as emerging infectious
diseases as well as potentially engineered biothreats. While many research efforts have been …