Background The metabolic basis of Alzheimer disease (AD) pathology and expression of AD
symptoms is poorly understood. Omega-3 and -6 fatty acids have previously been linked to …

Drilling-fluid densities vary significantly over wide ranges of temperature and pressure, a
concern that is particularly critical in deepwater, Arctic, and high-pressure/high-temperature. …

Drilling fluid density is typically provided by dense, homogenously-dispersed, fine solids.
Density fluctuations can occur if solids are no longer homogenously suspended. These …

INTRODUCTION: Three of the four treatments for Alzheimer’s disease are cholinesterase
inhibitors targeting the pathological reduction of acetylcholine levels. Here we aimed to …

Density profiles of brines and other well fluids are critical to determining true downhole static
pressures during completion, workover, and testing operations. Low-temperature conditions …

The complex and demanding set of requirements for high-pressure, high-temperature (HPHT)
deepwater environments is a big challenge for drilling fluid formulation1, 2. A variety of …

Three of the four treatments for Alzheimer's disease (Donepezil, Rivastigmine and Galantamine)
are cholinesterase inhibitors that target the pathological reduction of acetylcholine levels…

Perturbations in the microtubule‐associated protein tau occur in several human neurodegenerative
diseases. In Alzheimer's disease and progressive supranuclear palsy (PSP), tau …

Background Higher prostate cancer mortality rates among US immigrants from countries with
lower rates suggest environmental influences on prostate carcinogenesis (eg, diet, body …

BACKGROUND Prostate carcinoma exhibits considerable anatomic heterogeneity. Detailed
characterization of prostate carcinoma distribution could lead to improved detection …