Systematic comparison of single-cell and single-nucleus RNA-sequencing methods

…, MH Wadsworth, T Burks, LT Nguyen, JYH Kwon… - Nature …, 2020 - nature.com
The scale and capabilities of single-cell RNA-sequencing methods have expanded rapidly
in recent years, enabling major discoveries and large-scale cell mapping efforts. However, …

[HTML][HTML] A distinct gene module for dysfunction uncoupled from activation in tumor-infiltrating T cells

…, K Sakuishi, S Kurtulus, D Gennert, J Xia, JYH Kwon… - Cell, 2016 - cell.com
Reversing the dysfunctional T cell state that arises in cancer and chronic viral infections is
the focus of therapeutic interventions; however, current therapies are effective in only some …

Systematic comparative analysis of single cell RNA-sequencing methods

…, MH Wadsworth, T Burks, LT Nguyen, JYH Kwon… - BioRxiv, 2019 - biorxiv.org
A multitude of single-cell RNA sequencing methods have been developed in recent years,
with dramatic advances in scale and power, and enabling major discoveries and large scale …

Stepwise-edited, human melanoma models reveal mutations' effect on tumor and microenvironment

E Hodis, ET Triglia, JYH Kwon, T Biancalani, LR Zakka… - Science, 2022 - science.org
Establishing causal relationships between genetic alterations of human cancers and specific
phenotypes of malignancy remains a challenge. We sequentially introduced mutations into …

Primary open-angle glaucoma

YH Kwon, JH Fingert, MH Kuehn… - New England Journal …, 2009 - Mass Medical Soc
Primary Open-Angle Glaucoma | NEJM Skip to main content NEJM Group Follow Us Facebook
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[PDF][PDF] Retinal ganglion cell death in glaucoma: mechanisms and neuroprotective strategies.

MH Kuehn, JH Fingert, YH Kwon - development, 2005 - myweb.uiowa.edu
Neuroprotection can be defined as any therapeutic paradigm designed to prevent or delay
neuronal cell death and maintain neural function. In glaucoma, progressive death of the …

Application of calixarene to high active surface‐enhanced Raman scattering (SERS) substrates suitable for in situ detection of polycyclic aromatic hydrocarbons …

YH Kwon, K Sowoidnich, H Schmidt… - Journal of Raman …, 2012 - Wiley Online Library
The characteristics of the sol–gel matrix embedding Ag nanoparticles functionalized with 25,27‐dimercaptoacetic
acid‐26,28‐dihydroxy‐4‐tert‐butylcalix[4]arene (DMCX) suitable for …

Influence of surface plasmon resonance wavelength on SERS activity of naturally grown silver nanoparticle ensemble

YH Kwon, R Ossig, F Hubenthal… - Journal of Raman …, 2012 - Wiley Online Library
We present experimental results to quantify and optimize the surface‐enhanced Raman
scattering (SERS) activity of naturally grown silver nanoparticles. Ag nanoparticle ensembles …

Ginsenoside Rg3 inhibits endothelial progenitor cell differentiation through attenuation of VeGF‐dependent Akt/eNOS signaling

JW Kim, SY Jung, YH Kwon, SH Lee… - Phytotherapy …, 2012 - Wiley Online Library
Endothelial progenitor cells (EPCs) play a critical role both in vascular repair after cell
transplantation for ischemic diseases and in the growth of early tumors by intervening with the …

Development of drift design model for high‐rise buildings subjected to lateral and vertical loads

HS Park, JH Seo, YH Kwon - The Structural Design of Tall and …, 2008 - Wiley Online Library
Recent developments of resizing algorithms based on displacement participation factor have
had a significant impact on drift design of high‐rise buildings. However, most drift design …