There is a fast growing collection of data describing the structure and functional capacity of
the microbiome in a variety of conditions available to the research community for …

OBJECTIVES: Patients who are immunocompromised (IC) are at increased risk ofClostridium
difficileinfection (CDI), which has increased to epidemic proportions over the past decade. …

BACKGROUND & AIMS: Helicobacter pylori infection increases gastric regulatory T cell (Treg)
response, which may contribute to H pylori immune escape. We hypothesize that H pylori …

Background Epidemiologic data suggest a protective effect of Helicobacter pylori infection
against the development of autoimmune disease. Laboratory data illustrate H. pylori's ability to …

Candida albicans is a normal member of the gastrointestinal (GI) tract microbiota of healthy
humans, but during host immunosuppression or alterations in the bacterial microbiota, C. …

Background & Aims Rifaximin is used to treat patients with functional gastrointestinal disorders,
but little is known about its therapeutic mechanism. We propose that rifaximin modulates …

Despite guidelines for detection and treatment of Helicobacter pylori infection, recommendations
to test patients before and after therapy are commonly not followed in the United States. …

Background & Aims The efficacy of treatment of Helicobacter pylori infection has decreased
steadily because of increasing resistance to clarithromycin, metronidazole, and levofloxacin. …

Background & Aims Gut dysbiosis is closely involved in the pathogenesis of inflammatory
bowel disease (IBD). However, it remains unclear whether IBD-associated gut dysbiosis …

Background Dextran sodium sulfate (DSS) is used to induce murine colitis. Although the exact
mechanism by which DSS administration causes disease is unknown, evidence suggests …