[HTML][HTML] A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung
The lung contains numerous specialized cell types with distinct roles in tissue function and
integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a …
integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a …
[PDF][PDF] ATF4-induced warburg metabolism drives over-proliferation in Drosophila
S Sorge, J Theelke, K Yildirim, H Hertenstein… - Cell Reports, 2020 - cell.com
The mitochondrial electron transport chain (ETC) enables essential metabolic reactions;
nonetheless, the cellular responses to defects in mitochondria and the modulation of signaling …
nonetheless, the cellular responses to defects in mitochondria and the modulation of signaling …
[HTML][HTML] Local tissue interactions govern pLL patterning in medaka
…, K Gross, J Onistschenko, OP Hoang, J Theelke… - Developmental …, 2022 - Elsevier
Vertebrate organs are arranged in a stereotypic, species-specific position along the animal
body plan. Substantial morphological variation exists between related species, especially so …
body plan. Substantial morphological variation exists between related species, especially so …
Postnatal FGFR-signaling establishes gradients of secretory cell identities along the proximal-distal axis of the lung airways
A Sountoulidis, AB Firsova, A Liontos, J Theelke… - bioRxiv, 2023 - biorxiv.org
The spatial organization and developmental control of cell maturation in the branched
airway epithelium are only partially understood. Here, we labelled the major adult secretory …
airway epithelium are only partially understood. Here, we labelled the major adult secretory …
Developmental origins of cell heterogeneity in the human lung
…, J Bergenstråhle, M Vicari, P Czarnewski, J Theelke… - BioRXiv, 2022 - biorxiv.org
The lung contains numerous specialized cell-types with distinct roles in tissue function and
integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a …
integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a …
Topographic atlas of cell states identifies regional gene expression in the adult human lung
…, Z Andrusivova, A Sountoulidis, J Theelke… - 2024 - diva-portal.org
Single cell mRNA sequencing of the whole organ has become a popular technique to reveal
rare types and subtypes of previously characterized cells as well as to distinguish and …
rare types and subtypes of previously characterized cells as well as to distinguish and …
An ATF4-mediated transcriptional adaptation of electron transport chain disturbance primes progenitor cells for proliferation in vivo
S Sorge, J Theelke, C Altbürger, I Lohmann - bioRxiv, 2018 - biorxiv.org
The mitochondrial electron transport chain (ETC) enables many important metabolic
reactions, like ATP generation and redox balance. While the vital importance of mitochondrial …
reactions, like ATP generation and redox balance. While the vital importance of mitochondrial …
Molecular Determinants of Synaptic Specificity at the Single Cell Level
J Velten - 2021 - archiv.ub.uni-heidelberg.de
The correct wiring of neuronal circuits represents one of the most complex processes throughout
development. Mistakes in their formation underly genetic neuropathies including autism …
development. Mistakes in their formation underly genetic neuropathies including autism …
FGF-dependent mechanosensory organ patterning in zebrafish
A Nechiporuk, DW Raible - Science, 2008 - science.org
During development, organ primordia reorganize to form repeated functional units. In
zebrafish (Danio rerio), mechanosensory organs called neuromasts are deposited at regular …
zebrafish (Danio rerio), mechanosensory organs called neuromasts are deposited at regular …
[HTML][HTML] Evolutionary genetics of canine respiratory coronavirus and recent introduction into Swedish dogs
…, S Larsson, R van Damme, AK Theelke… - Infection, Genetics and …, 2020 - Elsevier
Canine respiratory coronavirus (CRCoV) has been identified as a causative agent of canine
infectious respiratory disease, an upper respiratory infection affecting dogs. The …
infectious respiratory disease, an upper respiratory infection affecting dogs. The …