User profiles for Jonathan C. Kao

Jonathan Kao

University of California, Los Angeles
Verified email at seas.ucla.edu
Cited by 3428

A high-performance neural prosthesis enabled by control algorithm design

…, JM Fan, MM Churchland, MT Kaufman, JC Kao… - Nature …, 2012 - nature.com
Neural prostheses translate neural activity from the brain into control signals for guiding
prosthetic devices, such as computer cursors and robotic limbs, and thus offer individuals with …

Inferring single-trial neural population dynamics using sequential auto-encoders

…, J Collins, R Jozefowicz, SD Stavisky, JC Kao… - Nature …, 2018 - nature.com
Neuroscience is experiencing a revolution in which simultaneous recording of thousands of
neurons is revealing population dynamics that are not apparent from single-neuron …

A recurrent neural network for closed-loop intracortical brain–machine interface decoders

D Sussillo, P Nuyujukian, JM Fan, JC Kao… - Journal of neural …, 2012 - iopscience.iop.org
Recurrent neural networks (RNNs) are useful tools for learning nonlinear relationships in time
series data with complex temporal dependences. In this paper, we explore the ability of a …

[HTML][HTML] Single-trial dynamics of motor cortex and their applications to brain-machine interfaces

JC Kao, P Nuyujukian, SI Ryu, MM Churchland… - Nature …, 2015 - nature.com
Increasing evidence suggests that neural population responses have their own internal drive,
or dynamics, that describe how the neural population evolves through time. An important …

[HTML][HTML] Making brain–machine interfaces robust to future neural variability

D Sussillo, SD Stavisky, JC Kao, SI Ryu… - Nature …, 2016 - nature.com
A major hurdle to clinical translation of brain–machine interfaces (BMIs) is that current decoders,
which are trained from a small quantity of recent data, become ineffective when neural …

A low-power band of neuronal spiking activity dominated by local single units improves the performance of brain–machine interfaces

…, H An, PP Vu, AJ Bullard, CS Nu, JC Kao… - Nature biomedical …, 2020 - nature.com
The large power requirement of current brain–machine interfaces is a major hindrance to
their clinical translation. In basic behavioural tasks, the downsampled magnitude of the 300–…

A high performing brain–machine interface driven by low-frequency local field potentials alone and together with spikes

SD Stavisky, JC Kao, P Nuyujukian… - Journal of neural …, 2015 - iopscience.iop.org
Objective. Brain–machine interfaces (BMIs) seek to enable people with movement disabilities
to directly control prosthetic systems with their neural activity. Current high performance …

Latent factors and dynamics in motor cortex and their application to brain–machine interfaces

…, A Farshchian, LE Miller, EL Dyer, JC Kao - Journal of …, 2018 - Soc Neuroscience
In the 1960s, Evarts first recorded the activity of single neurons in motor cortex of behaving
monkeys ( Evarts, 1968 ). In the 50 years since, great effort has been devoted to …

[PDF][PDF] Motor cortical visuomotor feedback activity is initially isolated from downstream targets in output-null neural state space dimensions

SD Stavisky, JC Kao, SI Ryu, KV Shenoy - Neuron, 2017 - cell.com
Neural circuits must transform new inputs into outputs without prematurely affecting
downstream circuits while still maintaining other ongoing communication with these targets. We …

Decoding and perturbing decision states in real time

…, R Kiani, JC Kao, P Nuyujukian, C Chandrasekaran… - Nature, 2021 - nature.com
In dynamic environments, subjects often integrate multiple samples of a signal and combine
them to reach a categorical judgment 1 . The process of deliberation can be described by a …