Context It has been well established that the human gut microbiome plays a critical role in
the regulation of important biological processes and the mechanisms underlying numerous …

Multi-omics studies, which explore the interactions between multiple types of biological factors,
have significant advantages over single-omics analysis for their ability to provide a more …

Bone marrow-derived mesenchymal stem cells (BM-MSCs) are multipotent stromal cells that
have a critical role in the maintenance of skeletal tissues such as bone, cartilage, and the …

Objective Many animal experiments and epidemiological studies have shown that the gut
microbiota (GM) plays an important role in the development of obesity, but the specific …

… Jonathan Greenbaum provided advice and suggestions while we met some problems
during the data analysis process. Wei Dong Zhang and Chang-Qing Sun gave constructive …

Background Both type 2 diabetes (T2D) and Alzheimer's disease (AD) occur commonly in
the aging populations and T2D has been considered as an important risk factor for AD. The …

Although the gut microbiota has been reported to influence osteoporosis risk, the individual
species involved, and underlying mechanisms, remain largely unknown. We performed …

Since coronavirus disease 2019 (COVID-19) is a serious new worldwide public health crisis
with significant morbidity and mortality, effective therapeutic treatments are urgently needed. …

Human osteoblasts are multifunctional bone cells, which play essential roles in bone
formation, angiogenesis regulation, as well as maintenance of hematopoiesis. However, the …

Background Lower rates of smoking cessation are a major reason for the higher prevalence
of smoking among socioeconomically disadvantaged adults. Because barriers to quitting …