Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system
Conventional methods for histopathologic tissue diagnosis are labor- and time-intensive
and can delay decision-making during diagnostic and therapeutic procedures. We report the …
and can delay decision-making during diagnostic and therapeutic procedures. We report the …
Efforts to make and apply humanized yeast
JM Laurent, JH Young, AH Kachroo… - Briefings in functional …, 2016 - academic.oup.com
Despite a billion years of divergent evolution, the baker’s yeast Saccharomyces cerevisiae
has long proven to be an invaluable model organism for studying human biology. Given its …
has long proven to be an invaluable model organism for studying human biology. Given its …
Metabolic markers and statistical prediction of serous ovarian cancer aggressiveness by ambient ionization mass spectrometry imaging
…, R Tibshirani, J Zhang, L Liang, J Liu, JH Young… - Cancer research, 2017 - AACR
Ovarian high-grade serous carcinoma (HGSC) results in the highest mortality among
gynecological cancers, developing rapidly and aggressively. Dissimilarly, serous borderline …
gynecological cancers, developing rapidly and aggressively. Dissimilarly, serous borderline …
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
[HTML][HTML] Genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
(WTCCC2) consortia is provided in the Supplementary Note online. Author Contributions FC,
ADB, CEMG, J. Kere., A. Reis, JNB and RCT oversaw cohort collection for both the …
ADB, CEMG, J. Kere., A. Reis, JNB and RCT oversaw cohort collection for both the …
[HTML][HTML] A scalable system for production of functional pancreatic progenitors from human embryonic stem cells
TC Schulz, HY Young, AD Agulnick, MJ Babin… - PloS one, 2012 - journals.plos.org
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will
require the translation of proof-of-principle concepts into a scalable, controlled, and …
require the translation of proof-of-principle concepts into a scalable, controlled, and …
Contagion in financial networks
P Glasserman, HP Young - Journal of Economic Literature, 2016 - aeaweb.org
The recent financial crisis has prompted much new research on the interconnectedness of the
modern financial system and the extent to which it contributes to systemic fragility. Network …
modern financial system and the extent to which it contributes to systemic fragility. Network …
The evolution of social norms
HP Young - economics, 2015 - annualreviews.org
… do not interact, or interact only occasionally, they may follow different evolutionary trajectories
and thus have different norms even though in other respects they are similar (Young 1998b…
and thus have different norms even though in other respects they are similar (Young 1998b…
[HTML][HTML] Interaction between genetic control of vascular endothelial growth factor production and retinoid responsiveness in psoriasis
HS Young, AM Summers, IR Read, DA Fairhurst… - Journal of investigative …, 2006 - Elsevier
Vascular endothelial growth factor (VEGF) promotes angiogenesis, and elevated levels are
found in plaques of psoriasis. Two VEGF polymorphisms, +405 and −460, are associated …
found in plaques of psoriasis. Two VEGF polymorphisms, +405 and −460, are associated …
Patterns, causes, and consequences of anthropocene defaunation
Anthropocene defaunation, the global extinction of faunal species and populations and the
decline in abundance of individuals within populations, has been predominantly documented …
decline in abundance of individuals within populations, has been predominantly documented …