Technologically critical rare-earth elements are notoriously difficult to separate, owing to their
subtle differences in ionic radius and coordination number 1 , 2 – 3 . The natural lanthanide…

Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous system.
While work has focused on myelin and axon loss in MS, less is known about mechanisms …

Recent studies indicate that cellular metabolism plays a key role in supporting immune cell
maintenance and development. Here, we review how metabolism guides immune cell …

CRISPR–Cas9 has emerged as a powerful technology that enables ready modification of
the mammalian genome. The ability to modulate Cas9 activity can reduce off-target cleavage …

Macrophages are activated during microbial infection to coordinate inflammatory responses
and host defense. Here we find that in macrophages activated by bacterial …

Studies of individual T cell antigen receptors (TCRs) have shed some light on structural
features that underlie self-reactivity. However, the general rules that can be used to predict …

Objective Patients with Niemann–Pick disease type C1 (NPC1), a lysosomal lipid storage
disorder that causes neurodegeneration and liver damage, can present with IBD, but neither …

Plant-based dietary patterns are associated with improved cardiometabolic health, but
causal dietary components are unclear. Protein has been proposed to play a role, but the …

This paper is composed of three self-consistent sections that can be read independently of
each other. In Sec. 1, we define and analyze the low Mach number problem through a linear …

Objective Following chronic liver injury or when hepatocyte proliferation is impaired, ductular
reactions containing hepatic progenitor cells (HPCs) appear in the periportal regions and …