User profiles for Jonathan Pettitt
Jonathan PettittReader in Genetics, University of Aberdeen Verified email at abdn.ac.uk Cited by 1895 |
Repression of gene expression in the embryonic germ lineage of C. elegans
THE distinction between soma and germline was recognized more than a century ago:
somatic cells form the body of an organism, whereas germ cells serve to produce future …
somatic cells form the body of an organism, whereas germ cells serve to produce future …
Cadherin superfamily proteins in Caenorhabditis elegans and Drosophila melanogaster
E Hill, ID Broadbent, C Chothia, J Pettitt - Journal of molecular biology, 2001 - Elsevier
The ability to form selective cell-cell adhesions is an essential property of metazoan cells.
Members of the cadherin superfamily are important regulators of this process in both …
Members of the cadherin superfamily are important regulators of this process in both …
The pogo transposable element family of Drosophila melanogaster
A 190 by insertion is associated with the white-eosin mutation in Drosophila melanogaster.
This insertion is a member of a family of transposable elements, pogo elements, which is of …
This insertion is a member of a family of transposable elements, pogo elements, which is of …
The Caenorhabditis elegans p120 catenin homologue, JAC-1, modulates cadherin–catenin function during epidermal morphogenesis
J Pettitt, EA Cox, ID Broadbent, A Flett… - The Journal of cell …, 2003 - rupress.org
The cadherin–catenin complex is essential for tissue morphogenesis during animal
development. In cultured mammalian cells, p120 catenin (p120ctn) is an important regulator of …
development. In cultured mammalian cells, p120 catenin (p120ctn) is an important regulator of …
[HTML][HTML] Bridging the phenotypic gap: Real-time assessment of mitochondrial function and metabolism of the nematode Caenorhabditis elegans
Background The ATP levels of an organism are an important physiological parameter that is
affected by genetic make up, ageing, stress and disease. Results We have generated …
affected by genetic make up, ageing, stress and disease. Results We have generated …
[HTML][HTML] People with more extreme attitudes towards science have self-confidence in their understanding of science, even if this is not justified
C Fonseca, J Pettitt, A Woollard, A Rutherford… - PLoS …, 2023 - journals.plos.org
People differ greatly in their attitudes towards well-evidenced science. What characterises
this variation? Here, we consider this issue in the context of genetics and allied sciences. …
this variation? Here, we consider this issue in the context of genetics and allied sciences. …
[HTML][HTML] Both trust in, and polarization of trust in, relevant sciences have increased through the COVID-19 pandemic
S Radrizzani, C Fonseca, A Woollard, J Pettitt… - Plos one, 2023 - journals.plos.org
While attempts to promote acceptance of well-evidenced science have historically focused
on increasing scientific knowledge, it is now thought that for acceptance of science, trust in, …
on increasing scientific knowledge, it is now thought that for acceptance of science, trust in, …
[HTML][HTML] The cadherin superfamily
J Pettitt - WormBook: The Online Review of C. Elegans Biology …, 2005 - ncbi.nlm.nih.gov
The cadherins are a major class of membrane proteins with prominent roles in cell adhesion,
and the regulation of tissue organisation and morphogenesis. The C. elegans genome …
and the regulation of tissue organisation and morphogenesis. The C. elegans genome …
cdh-3, a gene encoding a member of the cadherin superfamily, functions in epithelial cell morphogenesis in Caenorhabditis elegans
J Pettitt, WB Wood, RHA Plasterk - Development, 1996 - journals.biologists.com
Several genes that encode members of the cadherin super-family have been identified in
Caenorhabditis elegans. Based on the roles of cadherins in vertebrates and Drosophila, it is …
Caenorhabditis elegans. Based on the roles of cadherins in vertebrates and Drosophila, it is …
[PDF][PDF] A genome-wide functional screen shows MAGI-1 is an L1CAM-dependent stabilizer of apical junctions in C. elegans
…, A Couthier, M Cameron, I Chin-Sang, J Pettitt… - Current biology, 2012 - cell.com
Background In multicellular organisms, cell-cell junctions are involved in many aspects of
tissue morphogenesis. α-catenin links the cadherin-catenin complex (CCC) to the actin …
tissue morphogenesis. α-catenin links the cadherin-catenin complex (CCC) to the actin …