[PDF][PDF] Modulation of the promoter activation rate dictates the transcriptional response to graded BMP signaling levels in the Drosophila embryo
C Hoppe, JR Bowles, TG Minchington, C Sutcliffe… - Developmental cell, 2020 - cell.com
Morphogen gradients specify cell fates during development, with a classic example being
the bone morphogenetic protein (BMP) gradient's conserved role in embryonic dorsal-ventral …
the bone morphogenetic protein (BMP) gradient's conserved role in embryonic dorsal-ventral …
Scalable inference of transcriptional kinetic parameters from MS2 time series data
Motivation The MS2-MCP (MS2 coat protein) live imaging system allows for visualization of
transcription dynamics through the introduction of hairpin stem-loop sequences into a gene. …
transcription dynamics through the introduction of hairpin stem-loop sequences into a gene. …
Uncovering Transcriptional Bursting Dynamics From Spatially Resolved Single-Cell Microscopy Data
JR Bowles - 2022 - search.proquest.com
Recent advances in live imaging technology, such as the MS2-GFP system, have enabled
the recording of transcriptional data at the single-cell level at ever-greater temporal and …
the recording of transcriptional data at the single-cell level at ever-greater temporal and …
Uncovering transcriptional dynamics from spatially resolved single-cell microscopy data
JR Bowles - 2022 - escholar.manchester.ac.uk
Recent advances in live imaging technology, such as the MS2-GFP system, have enabled
the recording of transcriptional data at the single-cell level at ever-greater temporal and …
the recording of transcriptional data at the single-cell level at ever-greater temporal and …
A comparative study of ultrasonic micro-motors based on single crystal PMN-PT and polycrystalline PZT ceramics
…, PJ Rayner, J Gore, AR Bowles… - … of Smart Structures …, 2008 - spiedigitallibrary.org
A comparative study has been made to explore the potential benefits of newly available
single-crystal ferroelectric materials when used in a practical device, in this case an ultrasonic …
single-crystal ferroelectric materials when used in a practical device, in this case an ultrasonic …
Algorithms to guide ambulance clinicians in the management of emergencies in patients with implanted rotary left ventricular assist devices
CT Bowles, R Hards, N Wrightson, P Lincoln… - Emergency Medicine …, 2017 - emj.bmj.com
Advances in left ventricular assist device (LVAD) therapy have resulted in increasing numbers
of adult LVAD recipients in the community. However, device failure, stroke, bleeding, …
of adult LVAD recipients in the community. However, device failure, stroke, bleeding, …
Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine
Lower back and neck pain are leading physical conditions for which patients see their doctors
in the United States. The organ commonly implicated in this condition is the intervertebral …
in the United States. The organ commonly implicated in this condition is the intervertebral …
Immune boosting by B. 1.1. 529 (Omicron) depends on previous SARS-CoV-2 exposure
The Omicron, or Pango lineage B.1.1.529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …
Endogenous circadian system increases capacity for enhanced coronary microvascular function in the morning
Major adverse cardiovascular events occur more frequently in the morning. Cardiovascular
responses to typical morning behaviors, such as waking, standing, and increased physical …
responses to typical morning behaviors, such as waking, standing, and increased physical …
Self-assembly of aligned tissue-engineered annulus fibrosus and intervertebral disc composite via collagen gel contraction
Many cartilaginous tissues such as intervertebral disc (IVD) display a heterogeneous collagen
microstructure that results in mechanical anisotropy. These structures are responsible for …
microstructure that results in mechanical anisotropy. These structures are responsible for …