User profiles for Jonathan Z. Li

Jonathan Z Li

Brigham and Women's Hospital, Harvard Medical School
Verified email at bwh.harvard.edu
Cited by 14481

[HTML][HTML] Persistence and evolution of SARS-CoV-2 in an immunocompromised host

…, MS Seaman, M Cernadas, JZ Li - … England Journal of …, 2020 - Mass Medical Soc
SARS-CoV-2 in an Immunocompromised Host This letter describes an immunocompromised
patient who had persistent infection with SARS-CoV-2 over a period of months, despite …

[HTML][HTML] SARS-CoV-2 viral load is associated with increased disease severity and mortality

…, ET Ryan, E Gillespie, R Chishti, Y Li… - Nature …, 2020 - nature.com
The relationship between SARS-CoV-2 viral load and risk of disease progression remains
largely undefined in coronavirus disease 2019 (COVID-19). Here, we quantify SARS-CoV-2 …

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

…, IH Lee, Y Leng, ML Robinson, BM Sie, MZ Li… - Science, 2020 - science.org
INTRODUCTION A systematic characterization of the humoral response to severe acute
respiratory system coronavirus 2 (SARS-CoV-2) epitopes has yet to be performed. This analysis …

[HTML][HTML] Detection of SARS-CoV-2 with SHERLOCK one-pot testing

…, R Bruneau, MLW Huang, XG Yu, JZ Li… - … England Journal of …, 2020 - Mass Medical Soc
Detection of SARS-CoV-2 with a CRISPR-Based Test A new method for the detection of
SARS-CoV-2 combines simplified extraction of RNA with isothermal amplification and CRISPR (…

[PDF][PDF] Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19

…, X Sun, HJ Ticheli, MT Waring, AL Zhu, G Alter, JZ Li… - Cell, 2020 - cell.com
Humoral responses in coronavirus disease 2019 (COVID-19) are often of limited durability,
as seen with other human coronavirus epidemics. To address the underlying etiology, we …

[HTML][HTML] Duration of shedding of culturable virus in SARS-CoV-2 Omicron (BA. 1) infection

…, M Melberg, Y Li, RF Gilbert, Z Reynolds… - … England Journal of …, 2022 - Mass Medical Soc
Li, MD … Goldberg, JZ Li, Lemieux, Siedner, and Barczak) from the Massachusetts
Consortium for Pathogen Readiness , a grant (to Dr. Vyas) from the Massachusetts General …

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

…, WW Hannon, MC Choudhary, AS Dingens, JZ Li… - Science, 2021 - science.org
Antibodies are a potential therapy for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
but the risk of the virus evolving to escape them remains unclear. Here we map …

Persistent circulating severe acute respiratory syndrome coronavirus 2 spike is associated with post-acute coronavirus disease 2019 sequelae

Z Swank, Y Senussi, Z Manickas-Hill… - Clinical Infectious …, 2023 - academic.oup.com
The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an ongoing
medical challenge. To identify biomarkers associated with PASC we analyzed plasma …

Assessment of maternal and neonatal SARS-CoV-2 viral load, transplacental antibody transfer, and placental pathology in pregnancies during the COVID-19 …

AG Edlow, JZ Li, YC Ai-ris, C Atyeo, KE James… - JAMA network …, 2020 - jamanetwork.com
Importance Biological data are lacking with respect to risk of vertical transmission and
mechanisms of fetoplacental protection in maternal severe acute respiratory syndrome …

Pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): clinical presentation, infectivity, and immune responses

…, IV Bassett, D Irimia, AG Edlow, G Alter, JZ Li… - The Journal of …, 2020 - Elsevier
Objectives As schools plan for re-opening, understanding the potential role children play in
the coronavirus infectious disease 2019 (COVID-19) pandemic and the factors that drive …